Results 41 to 50 of about 305,587 (238)
Frontiers in Cell and Developmental Biology, 2022 Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles ...
Aoqi Li +3 more
doaj +1 more source
VE-cadherin and claudin-5: it takes two to tango [PDF]
, 2008 Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively.
A Taddei +17 more
core +5 more sources
Cell Reports, 2022 Summary: The mechanically activated Piezo channel plays a versatile role in conferring mechanosensitivity to various cell types. However, how it incorporates its intrinsic mechanosensitivity and cellular components to effectively sense long-range ...
Jing Wang +5 more
doaj
A toolkit for studying cell surface shedding of diverse transmembrane receptors
eLife, 2019 Proteolysis of transmembrane receptors is a critical cellular communication mechanism dysregulated in disease, yet decoding proteolytic regulation mechanisms of hundreds of shed receptors is hindered by difficulties controlling stimuli and unknown fates ...
Amanda N Hayward +2 more
doaj +1 more source
HIF-1α Contributes to Hypoxia-induced Invasion and Metastasis of Esophageal Carcinoma via Inhibiting E-cadherin and Promoting MMP-2 Expression [PDF]
, 2012 Hypoxia-inducible factor-1α (HIF-1α) has been found to enhance tumor invasion and metastasis, but no study has reported its action in esophageal carcinoma.
Cheng, Yun-Jie +7 more
core +1 more source
Journal of Cell Science, 2008 The cadherin molecules at adherens junctions have multiple isoforms. Cadherin isoform switching (cadherin switching) occurs during normal developmental processes to allow cell types to segregate from one another. Tumor cells often recapitulate this activity and the result is an aggressive tumor cell that gains the ability to leave the site of the tumor
Margaret J, Wheelock +4 more
openaire +2 more sources
eLife, 2021 Morphogenesis is governed by the interplay of molecular signals and mechanical forces across multiple length scales. The last decade has seen tremendous advances in our understanding of the dynamics of protein localization and turnover at subcellular ...
Robert J Huebner +5 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2019 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation
Frontiers in Molecular Neuroscience, 2018 Classical cadherins, a set of ~20 related recognition and signaling molecules, have been implicated in many aspects of neural development, including the formation and remodeling of synapses.
Masahito Yamagata +2 more
doaj +1 more source
The FAT1 Cadherin Drives Vascular Smooth Muscle Cell Migration
Cells, 2023 Vascular smooth muscle cells (VSMCs) are normally quiescent and non-migratory, regulating the contraction and relaxation of blood vessels to control the vascular tone.
Dario F. Riascos-Bernal +3 more
doaj +1 more source