Results 51 to 60 of about 321,674 (333)
Mechanisms of endothelial cell dysfunction in cystic fibrosis [PDF]
, 2017 Although cystic fibrosis (CF) patients exhibit signs of endothelial perturbation, the functions of the cystic fibrosis conductance regulator (CFTR) in vascular endothelial cells (EC) are poorly defined.
Anile, Marco +22 more
core +1 more source
Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression [PDF]
, 2010 Background: The development of teeth is the result of interactions between competent mesenchyme and epithelium, both of which undergo extensive morphogenesis.
Huysseune, Ann +3 more
core +3 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Genomic Locus Modulating IOP in the BXD RI Mouse Strains
G3: Genes, Genomes, Genetics, 2018 Intraocular pressure (IOP) is the primary risk factor for developing glaucoma, yet little is known about the contribution of genomic background to IOP regulation.
Rebecca King +4 more
doaj +1 more source
Differential Displacement of Classical Cadherins by VE-Cadherin [PDF]
Cell Communication & Adhesion, 2002 VE-cadherin is an endothelial cell-specific, type II classical cadherin that plays an important role in permeability, vasculogenesis, and vascular remodeling. Endothelial cells express equal levels of VE- and N-cadherin; VE-cadherin is present injunctions while N-cadherin is diffusely expressed over the surface of the cell.
Meena, Jaggi +2 more
openaire +2 more sources
Cell adhesion and cortex contractility determine cell patterning in the Drosophila retina
, 2007 Hayashi and Carthew (Nature 431 [2004], 647) have shown that the packing of cone cells in the Drosophila retina resembles soap bubble packing, and that changing E- and N-cadherin expression can change this packing, as well as cell shape.
A. F. M. Maree +28 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Frontiers in Synaptic Neuroscience, 2012 N-cadherin is a calcium-sensitive cell adhesion molecule commonly expressed at synaptic junctions and contributes to formation and maturation of synaptic contacts.
Richard J Flannery +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Matrix metalloproteinases, synaptic injury, and multiple sclerosis
Frontiers in Psychiatry, 2010 Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews. To follow,
Arek Szklarczyk, Katherine eConant
doaj +1 more source