Results 51 to 60 of about 305,587 (238)

Dysregulation of cadherins in the intercalated disc of the spontaneously hypertensive stroke-prone rat [PDF]

, 2010
The structural integrity of cardiac cells is maintained by the Ca2+-dependent homophilic cell-cell adhesion of cadherins. N-cadherin is responsible for this adhesion under normal physiological conditions.
Baker, Andrew, Craig, Margaret Anne, George, Sarah, McBride, Martin W., Smith, Godfrey   +4 more
core   +3 more sources

Pre-metazoan origins and evolution of the cadherin adhesome

Biology Open, 2014
Vertebrate adherens junctions mediate cell–cell adhesion via a “classical” cadherin–catenin “core” complex, which is associated with and regulated by a functional network of proteins, collectively named the cadherin adhesome (“cadhesome”). The most basal
Paul S. Murray, Ronen Zaidel-Bar
doaj   +1 more source

Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity [PDF]

, 2016
Background: Histone deacetylase inhibitors (HDACi) exert multiple cytotoxic actions on cancer cells. Currently, different synthetic HDACi are in clinical use or clinical trials; nevertheless, since both pro-invasive and anti-invasive activities have been
Andrade, Ricardo, Arluzea, Jon, Aréchaga, Juan, De Wever, Olivier, Díaz-Núñez, María, Díez-Torre, Alejandro, Silió, Margarita   +6 more
core   +4 more sources

Expression of Beta-Catenin, Cadherins and P-Runx2 in Fibro-Osseous Lesions of the Jaw: Tissue Microarray Study

Biomolecules, 2022
Fibrous dysplasia (FD) and hyperparathyroidism-jaw tumor syndrome (HPT-JT) are well-characterized benign bone fibro-osseous lesions. The intracellular mechanism leading to excessive deposition of fibrous tissue and alteration of differentiation processes
Giuseppe Pannone, Riccardo Nocini, Angela Santoro, Francesca Spirito, Pier Francesco Nocini, Silvana Papagerakis, Renny T. Franceschi, Marina Di Domenico, Angelina Di Carlo, Nana Danelia, Lorenzo Lo Muzio   +10 more
doaj   +1 more source

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo [PDF]

, 1991
Trunk neural crest cells and motor axons move in a segmental fashion through the rostral (anterior) half of each somitic sclerotome, avoiding the caudal (posterior) half.
Bronner-Fraser, Marianne, Ranscht, Barbara   +1 more
core  

Extending the host range of Listeria monocytogenes by rational protein design [PDF]

, 2007
SummaryIn causing disease, pathogens outmaneuver host defenses through a dedicated arsenal of virulence determinants that specifically bind or modify individual host molecules. This dedication limits the intruder to a defined range of hosts.
Deppenmeier, Stefanie, Gruber, Achim D, Heinz, Dirk W, Lengeling, Andreas, Pasche, Bastian, Rochon, Maike, Schubert, Wolf-Dieter, van den Heuvel, Joop, Wollert, Thomas   +8 more
core   +1 more source

Ready, set, differentiate! [PDF]

, 2013
The expression of E-Cadherin, a protein best known for its role in cell adhesion, regulates the onset of embryonic ...
Rodriguez, TA, Sancho, M
core   +2 more sources

Sirtuin 7 Promotes Mesenchymal to Epithelial Transition by β-Catenin Redistribution and Stabilization

Frontiers in Oncology, 2020
SIRT7 belongs to the family of “NAD+ dependent deacetylases” called Sirtuins. In the present work we report a novel role of SIRT7 in regulating cellular polarity.
Shashi Kiran, Shashi Kiran, Manjari Kiran, Manjari Kiran, Gayatri Ramakrishna   +4 more
doaj   +1 more source

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis. [PDF]

, 2017
During epithelial ovarian cancer (EOC) progression, intraperitoneally disseminating tumor cells and multicellular aggregates (MCAs) present in ascites fluid adhere to the peritoneum and induce retraction of the peritoneal mesothelial monolayer prior to ...
Alber, M, Kim, O, Klymenko, Y, Lombard, R, Loughran, E, Stack, MS, Yang, J   +6 more
core   +3 more sources

Dynamic Expression and Functional Implications of the Cell Polarity Gene, Dchs1, During Cardiac Development

Cells
Intercellular interactions among cardiac cell populations are essential for cardiac morphogenesis, yet the molecular mechanisms orchestrating these events remain incompletely understood.
Kathryn Byerly, Cayla Wolfe, Hannah Parris, Charlotte Griggs, Emily Wilson, Matthew Huff, Molly Griggs, Jordan Morningstar, Lilong Guo, Fulei Tang, Jan Guz, Taylor Petrucci, Ranan Phookan, Brian Loizzi, Cortney Gensemer, Russell A. Norris   +15 more
doaj   +1 more source