Results 71 to 80 of about 305,587 (238)
Cell adhesion is one of the basic phenomena occurring in a living organism, affecting many other processes such as proliferation, differentiation, migration, or cell viability.
Joanna Pastwińska+4 more
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Membrane-bound β-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. [PDF]
β-catenin has two different cellular functions: intercellular adhesion and transcriptional activity. The E3 ubiquitin ligase Siah1 causes ubiquitin-mediated degradation of the cytosolic β-catenin and therefore, impairs nuclear translocation and oncogenic
Bhattacharyya, A+7 more
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Rapid advances in combinatorial chemistry and molecular biology has influenced the discovery of many proteins, peptides and peptidomimetics as potential therapeutic agents.
Usman Sumo Friend Tambunan+5 more
doaj
It is well known that insect larval midgut cadherin protein serves as a receptor of Bacillus thuringiensis (Bt) crystal Cry1Ac or Cry1Ab toxins, since structural mutations and downregulation of cad gene expression are linked with resistance to Cry1Ac ...
Jianfeng Zhang+9 more
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Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]
The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C+3 more
core +1 more source
Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin). [PDF]
Endothelial cell proliferation is inhibited by the establishment of cell to cell contacts. Adhesive molecules at junctions could therefore play a role in transferring negative growth signals. The transmembrane protein VE-cadherin (vascular endothelial cadherin/cadherin-S) is selectively expressed at intercellular clefts in the endothelium.
Danielle Gulino+7 more
openaire +3 more sources
Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells
Many adult stem cells display prolonged quiescence, promoted by cues from their niche. Upon tissue damage, a coordinated transition to the activated state is required because non-physiological breaks in quiescence often lead to stem cell depletion and ...
Aviva J. Goel+4 more
doaj +1 more source
Sphingomyelin metabolism is involved in the differentiation of MDCK cells induced by environmental hypertonicity [PDF]
Sphingolipids (SLs) are relevant lipid components of eukaryotic cells. Besides regulating various cellular processes, SLs provide the structural framework for plasma membrane organization.
Favale, Nicolas Octavio+4 more
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Nomenclature of the desmosomal cadherins. [PDF]
Steinberg~§ * Laboratory of Eukaryotic Molecular Genetics, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom; ~New York University Medical Center, School of Medicine, New York University, New York 10016; §Institut fiir Zell- und Tumorbiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, Postfach 10 19 49,
BUXTON, RS+10 more
openaire +5 more sources
Expression patterns of chondrocyte genes cloned by differential display in tibial dyschondroplasia [PDF]
Tibial dyschondroplasia (TD) appears to involve a failure of the growth plate chondrocytes within growing long bones to differentiate fully to the hypertrophic stage, resulting in a mass of prehypertrophic chondrocytes which form the avascular TD lesion.
Botman, M+6 more
core +1 more source