Results 41 to 50 of about 136,487 (292)

Lamin-Binding Proteins in Caenorhabditis elegans

, 2016
The nuclear lamina, composed of lamins and numerous lamin-associated proteins, is required for mechanical stability, mechanosensing, chromatin organization, developmental gene regulation, mRNA transcription, DNA replication, nuclear assembly, and nuclear positioning.
Dobrzynska, Agnieszka, Askjaer, Peter, Gruenbaum, Yosef   +2 more
openaire   +3 more sources

Immunofluorescent Localization of Proteins in Caenorhabditis elegans Muscle [PDF]

, 2011
Caenorhabditis elegans is a premier model genetic system for discovering new information about the assembly and maintenance of striated muscle. The localization of a protein within a nematode muscle cell can reveal important clues to its function. In C.
Kristy J, Wilson, Hiroshi, Qadota, Guy M, Benian   +2 more
openaire   +2 more sources

CeLINC, a fluorescence-based protein–protein interaction assay in Caenorhabditis elegans [PDF]

Genetics, 2021
Abstract Interactions among proteins are fundamental for life and determining whether two particular proteins physically interact can be essential for fully understanding a protein’s function. We present Caenorhabditis elegans light-induced coclustering (CeLINC), an optical binary protein–protein interaction assay to determine whether
Jason R. Kroll, Sanne Remmelzwaal, Mike Boxem   +2 more
openaire   +3 more sources

RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. [PDF]

, 2019
Fam20C is a secreted protein kinase mutated in Raine syndrome, a human skeletal disorder. In vertebrates, bone and enamel proteins are major Fam20C substrates.
Adina Gerson-Gurwitz, Arribere, Arshad Desai, Bahl, Bando, Bies, Brown, Byerly, Cancino, Carolyn A. Worby, Carrascal, Cui, Dhanya Cheerambathur, Erin J. Cram, Fradin, Frøkjaer-Jensen, Gerald, Ghazarian, Gibson, Gorelik, Green, Ishikawa, Jack E. Dixon, Jeff Bouffard, Johnson, Kamath, Karen Oegema, Kian-Yong Lee, Kim, Kimble, Koike, Koob, Kovacevic, Köppen, Leiser, Leiser, Levin, Lindberg, Mann, Manning, Minko, Mody, Nakamura, Paschinger, Petrella, Pollak, Pollard, Pulvirenti, Raine, Reinhart, Renat Khaliullin, Rolls, Salvi, Sievers, Simpson, Sreelatha, Tagliabracci, Tagliabracci, Tagliabracci, Takeuchi, Tseng, Vogel, Wang, Ward, Wen, Wewer, Xiao, Yue, Zhang, Zhou, Zhou   +70 more
core   +3 more sources

Defective Mitochondrial Protein Translocation Precludes Normal Caenorhabditis elegans Development [PDF]

Journal of Biological Chemistry, 2004
We demonstrate biochemically that the genes identified by sequence similarity as orthologs of the mitochondrial import machinery are functionally conserved in Caenorhabditis elegans. Specifically, tin-9.1 and tin-10 RNA interference (RNAi) treatment of nematodes impairs import of the ADP/ATP carrier into isolated mitochondria.
Sean P, Curran, Edward P, Leverich, Carla M, Koehler, Pamela L, Larsen   +3 more
openaire   +2 more sources

Investigating hookworm genomes by comparative analysis of two Ancylostoma species [PDF]

, 2005
Background Hookworms, infecting over one billion people, are the mostly closely related major human parasites to the model nematode Caenorhabditis elegans.
Arasu, P., Clifton, S.W., Dante, M., Hawdon, J., Kapulkin, W., Martin, J., McCarter, J.P., Mitreva, M., Stajich, J.E., Waterston, R.H., Wilson, R.K., Wylie, T., Xu, J.   +12 more
core   +5 more sources

A systematic analysis of protein palmitoylation in Caenorhabditis elegans [PDF]

BMC Genomics, 2014
Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs).
Edmonds, Matthew J, Morgan, Alan
openaire   +2 more sources

RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan [version 4; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee   +10 more
doaj   +1 more source

An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development [PDF]

, 2007
Proper regulation of receptor tyrosine kinase (RTK)-Ras-mitogen-activated protein kinase (MAPK) signaling pathways is critical for normal development and the prevention of cancer.
Elgort, Marc G., Huang, Jingyu, Jongeward, Gregg, Lauritzen, Amara, Modzelewska, Katarzyna, Moghal, Nadeem, Sternberg, Paul W., Yoon, Charles H.   +7 more
core   +2 more sources