Results 141 to 150 of about 83,984 (318)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Caffeic acid treatment promotes the accumulation of flavonoids in fresh‐cut pineapple by histone lysine methylation regulation

open access: yesFood Frontiers
Fresh‐cut pineapple is highly popular with consumers, but it is also susceptible to quality deterioration during storage or shelf life. This study aimed to explore the effects of caffeic acid on the quality of fresh‐cut pineapple, specifically in ...
Jing Zeng   +10 more
doaj   +1 more source

Woollen fabric design with bioactive properties using Anatolian sweetgum tree (Liquidambar orientalis L.) leaves and fruits

open access: yesColoration Technology, EarlyView.
Abstract The recent focus among natural dyers is on identifying and utilising new natural dye sources. The current study explored the potential of the Anatolian sweetgum tree's leaves and fruits in providing bioactive properties with wool dyeing. In the dyeing process, iron (II) sulphate, alum, tannic acid and citric acid were used, and different ...
Hüseyin Benli   +3 more
wiley   +1 more source

From plant to fabric: Environmental opportunities associated with annatto dye for sustainable development in the textile industry

open access: yesColoration Technology, EarlyView.
Abstract Natural dyes are compounds that occur naturally in several organisms and are classified based on chemical structure and application method. The literature cites several natural dyes used in industrial transformation processes. Annatto dye is used in the food industry, and its biological pigment is extracted from the annatto seed. However, this
Marcel Jefferson Gonçalves   +5 more
wiley   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

open access: yesThe FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima   +11 more
wiley   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

Effects of Caffeic Acid and Its Derivatives on Bone: A Systematic Review

open access: yesDrug Design, Development and Therapy, 2021
Sophia Ogechi Ekeuku, Kok-Lun Pang, Kok-Yong Chin Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MalaysiaCorrespondence: Kok-Yong ChinDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan ...
Ekeuku SO, Pang KL, Chin KY
doaj  

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian   +2 more
wiley   +1 more source

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