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The Pluripotent Activities of Caffeic Acid Phenethyl Ester [PDF]

open access: yesMolecules, 2021
Caffeic acid phenethyl ester (CAPE) is a strong antioxidant extracted from honey bee-hive propolis. The mentioned compound, a well-known NF-κB inhibitor, has been used in traditional medicine as a potent anti-inflammatory agent. CAPE has a broad spectrum
Batoryna Olgierd   +3 more
doaj   +7 more sources

Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium [PDF]

open access: yesIranian Journal of Medical Sciences, 2023
Background: Tobacco smoke contains various toxins that negatively affect the human reproductive system. Caffeic acid phenethyl ester (CAPE), a potent antioxidant, has protective effects on the reproductive system against oxygen-free radicals ...
Amin Namdari, Behnoosh Miladpour
doaj   +4 more sources

Coassembly of Betulinol with Glycyrrhetinic Acid or Caffeic Acid Phenethyl Ester and Their Characteristics [PDF]

open access: yesACS Omega
Betulinol (Bet) is a bioactive pentacyclic triterpenoid with low water solubility. In this study, caffeic acid phenethyl ester (CAPE) and glycyrrhetinic acid (GA) were chosen as guest molecules to coassemble with Bet, and the characteristics of Bet-GA/CAPE coassemblies were investigated. The results show that the Bet-CAPE coassembly with a nanolamellar
Xin Chen   +4 more
doaj   +4 more sources

Caffeic acid phenethyl ester inhibits multispecies biofilm formation and cariogenicity [PDF]

open access: yesPeerJ
Background Caffeic acid phenethyl ester (CAPE), a natural phenolic compound, has demonstrated antibacterial effects. Dental caries etiology is multifactorial, including a cariogenic biofilm containing multispecies bacteria.
Paopanga Kokilakanit   +4 more
doaj   +5 more sources

Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives [PDF]

open access: yesMolecules, 2014
Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted
Pengxuan Zhang   +4 more
doaj   +5 more sources

Combination of Caffeic Acid Phenethyl Ester and Crocin Realign Potential Molecular Markers in U87-MG Glioma Cells [PDF]

open access: yesCurrent Therapeutic Research, 2023
: Background: Glial tumors are the most common primary malignant central nervous system tumors. They are hard to treat, not only because of the deregulation in multiple pathways but also because they are not contained in a well-defined mass with clear ...
Ashaq Hussain Mir, PhD   +4 more
doaj   +2 more sources

Therapeutic Impact of Caffeic Acid Phenethyl Ester and Acyclovir Combination on Human Gingival Fibroblasts (HGF-1) Infected With Herpes Simplex Type 1 ICP0. [PDF]

open access: yesMicrobiologyopen
ABSTRACT Herpes simplex virus Type 1 (HSV‐1) is a prevalent infectious agent globally, often causing oral infections like gingivostomatitis. The ICP0 protein of HSV‐1 exacerbates infection severity by inhibiting antiviral responses. Our study explored how combinations of CAPE (caffeic acid phenethyl ester) and acyclovir influenced immune responses in ...
Sen M, Celik S.
europepmc   +2 more sources

Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester

open access: yesActa Orthopaedica et Traumatologica Turcica, 2016
Abstract Keywords Matrix metalloproteinases; Caffeic acid phenethyl ester; Bone resorption <div id="\&quot;SD_BA1P\&quot;" class="\&quot;sgfNoTitleBar" sgfnogadgetborder="" svdonotlink="" ui-sortable\"="">
Sumeyya Akyol   +2 more
doaj   +6 more sources

“One Pot” Enzymatic Synthesis of Caffeic Acid Phenethyl Ester in Deep Eutectic Solvent [PDF]

open access: yesBiomolecules
Caffeic acid phenethyl ester (CAPE) represents a valuable ester of caffeic acid, which, over time, has demonstrated remarkable pharmacological properties. In general, the ester is obtained in organic solvents, especially by the esterification reaction of
Maria Roberta Tripon   +4 more
doaj   +2 more sources

Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties [PDF]

open access: yesFEBS Letters, 1993
Caffeic acid phenethyl ester, an active component of propolis extract, inhibits 5‐lipoxygenase in the micromolar concentration range. The inhibition is of an uncompetitive type, i.e. the inhibitor binds to the enzyme‐substrate complex but not to the free enzyme. Caffeic acid phenethyl ester also exhibits antioxidant properties. At a concentration of 10
Galina F Sud'Ina   +2 more
exaly   +3 more sources

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