The Pluripotent Activities of Caffeic Acid Phenethyl Ester [PDF]
Molecules, 2021 Caffeic acid phenethyl ester (CAPE) is a strong antioxidant extracted from honey bee-hive propolis. The mentioned compound, a well-known NF-κB inhibitor, has been used in traditional medicine as a potent anti-inflammatory agent. CAPE has a broad spectrum
Batoryna Olgierd +3 more
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Caffeic Acid Phenethyl Ester (CAPE): Biosynthesis, Derivatives and Formulations with Neuroprotective Activities [PDF]
Antioxidants, 2023 Neurodegenerative disorders are characterized by a progressive process of degeneration and neuronal death, where oxidative stress and neuroinflammation are key factors that contribute to the progression of these diseases.
Rebeca Pérez +10 more
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Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium [PDF]
Iranian Journal of Medical Sciences, 2023 Background: Tobacco smoke contains various toxins that negatively affect the human reproductive system. Caffeic acid phenethyl ester (CAPE), a potent antioxidant, has protective effects on the reproductive system against oxygen-free radicals ...
Amin Namdari, Behnoosh Miladpour
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Combination of Caffeic Acid Phenethyl Ester and Crocin Realign Potential Molecular Markers in U87-MG Glioma Cells [PDF]
Current Therapeutic Research, 2023 : Background: Glial tumors are the most common primary malignant central nervous system tumors. They are hard to treat, not only because of the deregulation in multiple pathways but also because they are not contained in a well-defined mass with clear ...
Ashaq Hussain Mir, PhD +4 more
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Caffeic Acid Phenethyl Ester and Caffeamide Derivatives Suppress Oral Squamous Cell Carcinoma Cells. [PDF]
Int J Mol Sci, 2023 Caffeic acid phenethyl ester (CAPE) contains antibiotic and anticancer activities. Therefore, we aimed to investigate the anticancer properties and mechanisms of CAPE and caffeamide derivatives in the oral squamous cell carcinoma cell (OSCC) lines SAS ...
Shih YH +9 more
europepmc +2 more sources
Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells. [PDF]
Molecules, 2023 Caffeic acid phenethyl ester (CAPE) belongs to the phenols found in propolis. It has already shown strong antiproliferative, cytotoxic and pro-apoptotic activities against head and neck cancers and against breast, colorectal, lung and leukemia cancer ...
Kleczka A, Dzik R, Kabała-Dzik A.
europepmc +2 more sources
Therapeutic Impact of Caffeic Acid Phenethyl Ester and Acyclovir Combination on Human Gingival Fibroblasts (HGF-1) Infected With Herpes Simplex Type 1 ICP0. [PDF]
MicrobiologyopenABSTRACT Herpes simplex virus Type 1 (HSV‐1) is a prevalent infectious agent globally, often causing oral infections like gingivostomatitis. The ICP0 protein of HSV‐1 exacerbates infection severity by inhibiting antiviral responses. Our study explored how combinations of CAPE (caffeic acid phenethyl ester) and acyclovir influenced immune responses in ...
Sen M, Celik S.
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Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway. [PDF]
Int J Mol Med, 2022 Osteoarthritis (OA) is the most common degenerative disease affecting the joints, and inflammation appears to play a critical role in the initiation and progression of OA.
Sun W +9 more
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“One Pot” Enzymatic Synthesis of Caffeic Acid Phenethyl Ester in Deep Eutectic Solvent [PDF]
BiomoleculesCaffeic acid phenethyl ester (CAPE) represents a valuable ester of caffeic acid, which, over time, has demonstrated remarkable pharmacological properties. In general, the ester is obtained in organic solvents, especially by the esterification reaction of
Maria Roberta Tripon +4 more
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Caffeic Acid Phenethyl Ester Loaded PEG-PLGA Nanoparticles Enhance Wound Healing in Diabetic Rats. [PDF]
Antioxidants (Basel), 2022 Delayed wound healing is a serious complication of diabetes and a main reason for foot amputation. Caffeic acid phenethyl ester (CAPE) is a main active constituent of honeybee propolis with reported appealing pharmacological activities.
Nasrullah MZ.
europepmc +2 more sources