Caffeic acid phenethyl ester inhibits multispecies biofilm formation and cariogenicity [PDF]
Background Caffeic acid phenethyl ester (CAPE), a natural phenolic compound, has demonstrated antibacterial effects. Dental caries etiology is multifactorial, including a cariogenic biofilm containing multispecies bacteria.
Paopanga Kokilakanit +4 more
doaj +5 more sources
Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives [PDF]
Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted
Pengxuan Zhang +4 more
doaj +5 more sources
Coassembly of Betulinol with Glycyrrhetinic Acid or Caffeic Acid Phenethyl Ester and Their Characteristics [PDF]
Betulinol (Bet) is a bioactive pentacyclic triterpenoid with low water solubility. In this study, caffeic acid phenethyl ester (CAPE) and glycyrrhetinic acid (GA) were chosen as guest molecules to coassemble with Bet, and the characteristics of Bet-GA/CAPE coassemblies were investigated. The results show that the Bet-CAPE coassembly with a nanolamellar
Xin Chen +4 more
doaj +4 more sources
Host-Guest Interactions of Caffeic Acid Phenethyl Ester with β-Cyclodextrins: Preparation, Characterization, and In Vitro Antioxidant and Antibacterial Activity. [PDF]
The aim of this study is to improve the solubility, chemical stability, and in vitro biological activity of caffeic acid phenethyl ester (CAPE) by forming inclusion complexes with β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (Hβ-CD) using the ...
Acar T +6 more
europepmc +2 more sources
Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID-19, and radiotherapy. [PDF]
Caffeic acid phenethyl ester (CAPE), a main active component of propolis and a flavonoid, is one of the natural products that has attracted attention in recent years.
Taysi S +3 more
europepmc +2 more sources
Thymoquinone and caffeic acid phenethyl ester mitigate experimental ulcerative colitis: a biochemical and histopathological study [PDF]
Purpose: To establish an acetic acid-induced acute ulcerative colitis model in rats and to evaluate the clinical, biochemical, and histopathological effects of thymoquinone (TQ) and caffeic acid phenethyl ester (CAPE) in this model.
Can Ersak +4 more
doaj +2 more sources
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway. [PDF]
The treatment of spinal cord injury (SCI) has always been a significant research focus of clinical neuroscience, with inhibition of microglia-mediated neuro-inflammation as well as oxidative stress key to successful SCI patient treatment.
Zhang Y +5 more
europepmc +2 more sources
Salivary levels of interleukin-8 (IL-8) are elevated in patients with periodontitis. Caffeic acid phenethyl ester (CAPE) improves the periodontal status in subjects. However, whether CAPE can reduce IL-8 expression is unclear.
Jie-Sian Wang +2 more
exaly +2 more sources
Methamphetamine (METH) is a highly abused substance on a global scale and has the capacity to elicit toxicity within the central nervous system. The neurotoxicity induced by METH encompasses neuronal degeneration and cellular demise within the substantia
Bin Yang +8 more
doaj +2 more sources
Redox-Responsive Crosslinked Mixed Micelles for Controllable Release of Caffeic Acid Phenethyl Ester. [PDF]
We report the elaboration of redox-responsive functional micellar nanocarriers designed for triggered release of caffeic acid phenethyl ester (CAPE) in cancer therapy.
Kamenova K +3 more
europepmc +2 more sources

