The phenolic‐rich aqueous extract of Cistus albidus leaves (CAAE) demonstrated significant antihyperglycemic activity in alloxan‐induced diabetic rats through improved glucose tolerance and modulation of metabolic biomarkers. CAAE also exerted lipid‐lowering and hepatoprotective effects, alongside notable α‐amylase inhibitory activity supported by ...
Aziz Zouhri +14 more
wiley +1 more source
Caffeic acid-related gene expression and antioxidant activity enhance drought tolerance in three bean cultivars. [PDF]
Rashidi Z, Azizi K, Eisvand HR.
europepmc +1 more source
UPLC‐ESI/HRMS profiling of the mangrove species Sonneratia caseolaris identified 45 metabolites in leaves and roots, mainly flavonoid glycosides, gallotannins, and other polyphenols, including two sulfated flavonoids not previously reported in mangroves.
Federico Cerri +5 more
wiley +1 more source
Elucidating the multiscale mechanisms and therapeutic targets of caffeic acid in gastric cancer: a synergy of computational and experimental approaches. [PDF]
Zhang H, Li Y, Li Y.
europepmc +1 more source
Thymus serpyllum (wild thyme) contains bioactive compounds such as carvacrol, thymol, β‐caryophyllene, γ‐terpinene, and α‐thujene, along with essential vitamins and minerals. These constituents exhibit antioxidant, antimicrobial, anti‐inflammatory, and antidiabetic activities.
Ahmad Mujtaba Noman +8 more
wiley +1 more source
Integrated Metabolomics and Transcriptomics Analyses Reveal the Critical Role of Caffeic Acid in Potato (<i>Solanum tuberosum</i> L.) Cold Tolerance. [PDF]
Li X +7 more
europepmc +1 more source
This study evaluated KDZ aqueous extract's therapeutic potential for MI/RI and investigated its mechanism. In a mouse MI/RI model, the aqueous extract mitigated injury and preserved cardiac function. Liquid chromatography‐mass spectrometry (LC–MS) identified eighty‐six components. Based on Compound‐target‐disease interaction network and KEGG enrichment
Xiaoxia Tian +7 more
wiley +1 more source
Targeting in vitro vasculogenic mimicry and associated stemness transcriptional signature in human ovarian cancer cell models: new emerging roles of caffeic acid phenethyl ester synthetic analogs. [PDF]
Touaibia M +4 more
europepmc +1 more source
This study successfully optimized the extraction parameters for Turkish bee bread using Response Surface Methodology (RSM) with a Central Composite Design (CCD). Under optimized conditions (30°C, 40 mL/g ratio, 66.7% ethanol, 20 h), the recovery of total phenolics (26.86 mg GAE/g) and flavonoids was maximized.
Nilay Keyvan +6 more
wiley +1 more source
Enhanced salinity stress tolerance and growth promotion in Melissa officinalis using caffeic acid nanocomposites as a promising nano-bio-based strategy. [PDF]
Ranjbar L +3 more
europepmc +1 more source

