Results 101 to 110 of about 12,490 (282)

分子経路の理解と治療を目指したハイポキシアの制御に関する研究 [PDF]

, 2018
筑波大学 (University of Tsukuba ...
Bhargava Priyanshu
core   +1 more source

Molecular pharmacology of rosmarinic and salvianolic acids: Potential seeds for Alzheimer’s and vascular dementia drugs. [PDF]

, 2018
Both caffeic acid and 3,4-dihydroxyphenyllactic acid (danshensu) are synthesized through two distinct routs of the shikimic acid biosynthesis pathway. In many plants, especially the rosemary and sage family of Lamiaceae, these two compounds are joined ...
Bose, Chen, Gu, Haas, Habtemariam, Habtemariam, Habtemariam, Jha, Juan-Badaturugea, Moosavi, Riemens, Scarpati, Solomon Habtemariam, Tang, Wang, Zhu   +15 more
core   +2 more sources

Beer Production With Umbu (Spondias tuberosa) Using Conventional and Nonconventional Yeast

Journal of Food Science, Volume 91, Issue 1, January 2026.
ABSTRACT This study evaluated the fermentation performance and bioactive properties of beers produced by Pichia kluyveri L131 and commercial Saccharomyces pastorianus, individually and in coculture, in wort enriched with umbu pulp. Fermentation profiles were assessed over 12 days, focusing on yeast population dynamics, carbohydrate consumption, and ...
Diego Pádua de Almeida, Hygor Lendell Silva de Souza, Ana Luiza Dozol, Mariana Moysés Delorme, Vanessa Naciuk Castelo‐Branco, Adriene Ribeiro Lima, Alexandre Soares dos Santos, Nadia Nara Batista, Rosane Freitas Schwan, Gustavo Molina, Cintia Lacerda Ramos   +10 more
wiley   +1 more source

Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

Exploration, Volume 5, Issue 6, December 2025.
1. Caffeic acid (CA) is a novel senomorphic. 2. Annexin A5 is the direct protein target of CA in senescent cells. 3. The covalent binding of CA to Annexin A5 protein triggers its degradation, PKCθ deactivation, and the inhibition of the NF‐κB inflammatory pathway. 4. CA effectively alleviates inflammation and lung fibrosis in mouse model.
Yinhua Zhu, Ying Zhang, Qianyu Zhang, Ping Song, Junzhe Zhang, Ang Ma, Chen Wang, Peng Gao, Tong Yang, Lirun Zhou, Qiaoli Shi, Yin Kwan Wong, Yongting Luo, Huan Tang, Jigang Wang   +14 more
wiley   +1 more source

Benefits of Nutrients and Phytonutrients in Nuts and Legumes on Platelet Aggregation Through DNA Methylation

Molecular Nutrition &Food Research, Volume 69, Issue 24, December 2025.
Nuts and legumes contain both nutrients and bioactive compounds supporting cardiovascular health related to influencing DNA methylation. These foods are related to reducing oxidative stress, supplying methyl donors, and modulating genes involved in platelet function, such as PEAR1 and mitochondrial genes, in association with helping reduce inflammation
Siwaphorn Chaimati, Jintana Sirivarasai, Nareerat Sutjarit   +2 more
wiley   +1 more source

Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment

Stem Cell Research & Therapy, 2017
Background Several studies have suggested that caffeic acid phenethyl ester (CAPE) can induce the expression of hypoxia inducible factor-1α (HIF-1α) protein.
Xiaofang Chen, Yi Han, Bowen Zhang, Yiming Liu, Sihan Wang, Tuling Liao, Ziliang Deng, Zeng Fan, Jing Zhang, Lijuan He, Wen Yue, Yanhua Li, Xuetao Pei   +12 more
doaj   +1 more source

Caffeic Acid Phenyl Ester (CAPE) Protects against Iron-Mediated Cellular DNA Damage through Its Strong Iron-Binding Ability and High Lipophilicity

Antioxidants, 2021
Caffeic acid phenethyl ester (CAPE) and its structurally-related caffeic acid (CA), ferulic acid (FA) and ethyl ferulate (EF) are constituents of honeybee propolis that have important pharmacological activities. This study found that CAPE—but not CA, FA,
Bo Shao, Li Mao, Miao Tang, Zhu-Ying Yan, Jie Shao, Chun-Hua Huang, Zhi-Guo Sheng, Ben-Zhan Zhu   +7 more
doaj   +1 more source

Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage

Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc, Serap Özer Yaman, Şafak Ersöz, Sevgi Kolaylı   +3 more
wiley   +1 more source

Water-Mediated Synthesis of (E)-3-(1-Methyl-1H-benzo[d]imidazol-5-yl)-N-phenethylacrylamide, a Caffeic Acid Phenethyl Amide Analogue

Molbank
Caffeic acid phenethyl ester (CAPE) is a phenolic natural product with diverse biological activities, notably anticancer properties. However, its ester group is metabolically unstable.
Muppidi Subbarao, Sean M. Kerwin
doaj   +1 more source

Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes

PPAR Research, 2016
Hypertrophic obesity inhibits activation of peroxisome proliferators-activated receptor gamma (PPARγ), considered the key mediator of the fully differentiated and insulin sensitive adipocyte phenotype.
Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo   +9 more
doaj   +1 more source