Results 61 to 70 of about 26,527 (265)

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Using caffeine on the patients as therapeutic option against treatment-resistant obsessive-compulsive disorder

Journal of Family Medicine and Primary Care, 2019
Obsessive-compulsive disorder (OCD) is one of the most common and debilitating diseases. Approximately 40-30% of these patients are resistant to treatment, which auxiliary drugs are used to treat these patients. One of these drugs is caffeine, which is capable of affecting adenosine receptors and interfering with its release and serotonin reuptake ...
Jamal Shams, Elahe Samadi Soufi, Alireza Zahiroddin, Reza Shekarriz-Foumani   +3 more
openaire   +3 more sources

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Non-Genetic Risk Factors for Parkinson’s Disease: An Overview of 46 Systematic Reviews

Journal of Parkinson’s Disease, 2021
Background: Numerous systematic reviews (SRs) and meta-analyses on non-genetic risk factors for Parkinson’s disease (PD) development have been published with inconsistent conclusions.
Yancong Chen, Xuemei Sun, Yali Lin, Zixuan Zhang, Yinyan Gao, Irene X.Y. Wu   +5 more
doaj   +1 more source

The Effectiveness of Caffeine (Rescuecaf) in Craving Reduction and Relapse Prevention in Methamphetamine Use Disorder: A Randomized Double-Blind, Placebo-Controlled Clinical Trial

Iranian Journal of Psychiatry and Behavioral Sciences, 2023
Background: One of the most critical public health issues in psychiatric and medical concerns is methamphetamine (METH) dependence. Objectives: The present study aimed to investigate caffeine (Rescuecaf) effectiveness in reducing craving and relapse prevention in METH dependence. Methods: In this double-blind, randomized clinical trial, 15 participants
Hedayat Sahraei, Jamal Shams, Razeyeh Eftekharzadeh, Ali Hosseinzadeh Oskouei, Seyed Mohsen Foroutan, Alireza Zahiroddin   +5 more
openaire   +1 more source

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard, Laura Farach, Hope Northrup, Sarah L. Wilson, Deborah Pearson, Syed Hashmi, Kate Richardson   +6 more
wiley   +1 more source

The Correlation of Individual Factors with High Blood Pressure of Industrial Painters at a Land Transportation Manufacturing Company

Jurnal Kesehatan Lingkungan, 2021
Introduction: The use of lead-based paint in the manufacturing process on land transportation production contributed to the decline of ambient air quality.
Emmanuella Dyca Novayanti, Benny Dwi Prasetyo   +1 more
doaj   +1 more source

Caffeine, chocolate, and adenosine antagonism in Parkinson's disease [PDF]

, 2022
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. It is generally accepted that dopamine replacement therapy substantially improves motor symptoms; however, there is a worldwide tendency to include nutrients in treatment ...
Reichmann, Heinz
core  

Caffeine use disorder and analgesic dependence in medication-overuse headache: insights into an underrecognized relationship

Frontiers in Neurology
BackgroundCaffeine plays a dual role in headache disorders, acting as an analgesic adjuvant while potentially contributing to headache chronification.
Rehab Magdy, Amr Hassan, Mona Hussein, Alaa Elmazny, Alaa Elmazny, Osama Yacoub, Mohamed Abdelghaffar, Nourhan Abdelmohsen Taha, Ahmed Essmat, May M. Fayez, Nahla Merghany, Anas Elgenidi, Anas Elgenidi, Ahmed Dahshan   +13 more
doaj   +1 more source

Morningness-eveningness and caffeine consumption: a largescale path-analysis study [PDF]

, 2019
It is still not clear how chronotype influences caffeine consumption (CC) and caffeine use disorder (CUD). The aim of the study was to investigate the relationship between chronotype, CC, CUD, and wellbeing. Participants of an online survey in Hungary (N
Demetrovics, Zsolt, Ágoston, C, Urbán, R, Griffiths, Mark D., Urbán, Róbert, Rigó, Adrien, Griffiths, MD, Demetrovics, Z, Rigó, A, Ágoston, Csilla   +9 more
core   +1 more source