Results 171 to 180 of about 12,684 (226)

Natural products as potential anticonvulsants: Caffeoylquinic acids

Archives of Pharmacal Research, 2012
Current anticonvulsant therapies are generally directed at symptomatic treatment by suppressing excitability within the brain. Consequently, they have adverse effects such as cognitive impairment, dependence, and abuse. The need for more effective and less toxic anticonvulsants has generated renewed interest in natural products for the treatment of ...
Hyo Geun, Kim, Myung Sook, Oh
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Caffeoylquinic Acids: Separation Method, Antiradical Properties and Cytotoxicity

Chemistry & Biodiversity, 2019
AbstractTwelve chlorogenic acid derivatives and two flavones were isolated from Moquiniastrum floribundum (Asteraceae, other name: Gochnatia floribunda). Compounds were evaluated in relation to their cytotoxicity and antiradical properties. Cytotoxicity was not observed for compounds, however, chlorogenic acid derivatives showed antiradical activity ...
Cinthia Indy Tamayose, Evelyne A. dos Santos, Nádia Roque, Letícia V. Costa‐Lotufo, Marcelo J. Pena Ferreira   +4 more
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Molecular docking of chlorogenic acid, 3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid with human serum albumin

Journal of Chinese Integrative Medicine, 2012
To investigate the mechanism of binding of human serum albumin (HSA) with potential sensitinogen, including chlorogenic acid and two isochlorogenic acids (3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid).By using the docking algorithm of computer-aided molecular design and the Molegro Virtual Docker, the crystal structures of HSA with ...
Jing, Zhou, Hong-yue, Ma, Xin-sheng, Fan, Wei, Xiao, Tuan-jie, Wang   +4 more
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Antioxidative Caffeoylquinic Acids and Flavonoids from Hemerocallis fulva Flowers

Journal of Agricultural and Food Chemistry, 2011
Tumor necrosis factor-α (TNF-α)-induced reactive oxygen species (ROS) production in HepG2 was used to screen hepatocyte protective compounds from the flowers of Hemerocallis fulva. Three new polyphenols, n-butyl 4-trans-O-caffeoylquinate (1), kaempferol 3-O-{α-L-rhamnopyranosyl(1→6)[α-L-rhamnopyranosyl(1→2)]}-β-D-galactopyranoside (2), and chrysoeriol ...
Yun-Lian, Lin, Chung-Kuang, Lu, Yeh-Jeng, Huang, Hong-Jhang, Chen   +3 more
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Caffeoylquinic Acids in Centella asiatica Protect against Amyloid-β Toxicity [PDF]

Journal of Alzheimer's Disease, 2014
The accumulation of amyloid-β (Aβ) is a hallmark of Alzheimer's disease and is known to result in neurotoxicity both in vivo and in vitro. We previously demonstrated that treatment with the water extract of Centella asiatica (CAW) improves learning and memory deficits in Tg2576 mice, an animal model of Aβ accumulation.
Nora E, Gray, Jeff, Morré, Jeremiah, Kelley, Claudia S, Maier, Jan F, Stevens, Joseph F, Quinn, Amala, Soumyanath   +6 more
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1,3,5-Tri-O-caffeoylquinic acid from Xanthium strumarium

Phytochemistry, 1993
Abstract A new polyphenol, 1,3,5-tri- O -caffeoylquinic acid, accompanied by 3,5-di- O -caffeoylquinic acid, has been isolated from the fruit of Xanthium strumarium .
Isao Agata, Saori Goto, Tsutomu Hatano, Sansei Nishibe, Takuo Okuda   +4 more
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Tissue age and caffeoylquinic acid concentration in sunflower

Phytochemistry, 1970
Abstract Through the use of one-dimensional paper chromatographic separation, followed by spectro-photometric analysis, chlorogenic acid, neochlorogenic acid and 4- O -caffeoylquinic acid concentrations have been determined in sections of field-grown Helianthus annuus L.
D.E. Koeppe, L.M. Rohrbaugh, E.L. Rice, S.H. Wender   +3 more
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Microencapsulation of a Natural Antioxidant from Coffee—Chlorogenic Acid (3-Caffeoylquinic Acid)

Food and Bioprocess Technology, 2017
Chlorogenic acids, the main polyphenolic group present in coffee, which include the caffeoylquinic acids, are recognized as antioxidants with growing interest in pharmacological, cosmetic, and food applications. However, they can be easily oxidized and they are also very unstable when exposed to high temperatures.
Bruna Gonçalves, M. Moeenfard, Fernando Rocha, Arminda Alves, Berta Nogueiro Estevinho, Lúcia Santos   +5 more
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In vivo deodorisation with caffeoylquinic acid derivatives

2006
Ku-ding-cha contained a large amount of the caffeoyl quinic acid (CQA) derivatives, di-CQA, 16.7% in dry weight as well as mono-CQA, 9.2%. A mixture of 3,5-DiCQA and 5-CQA with an apple acetone powder (AP), containing polyphenol oxidase, showed high capturing activities towards methanethiol (MeSH), propanethiol (PrSH), and 2-propenethiol (AllSH).
Osamu Negishi, Yukiko Negishi
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