Results 91 to 100 of about 5,149,759 (252)

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Hutchinson-Gilford progeria syndrome with severe calcific aortic valve stenosis and calcific mitral valve

, 2004
The case of a 12-year-old girl with clinical features of progeria with severe calcific valvar aortic stenosis is presented. The mitral valve showed the presence of calcium, and peripheral vascular disease was also present, though there was no family ...
Dora, S, Nair, K, Krishnamoorthy, KM, Achuthan, TJ, Ramachandran, P   +4 more
core   +1 more source

Human Aortic Valve Interstitial Cells Display Proangiogenic Properties During Calcific Aortic Valve Disease

, 2020
International audienceObjective: The study’s aim was to analyze the capacity of human valve interstitial cells (VICs) to participate in aortic valve angiogenesis.
Gaussem, Pascale, Rossi, Elisa, van Belle, Eric, Idelcadi, Salim, Cholley, Bernard, Rancic, Jeanne, Lecourt, Séverine, Jashari, Ramadan, Pamart, Thibault, Cras, Audrey, Bièche, Ivan, Susen, Sophie, Rosa, Mickael, Gendron, Nicolas, Staels, Bart, Sottejeau, Yoann, Vincentelli, André, Baudouin, Yaël, Carpentier, Alain, Chocron, Richard, Blandinieres, Adeline, Smadja, David, Dupont, Annabelle, Nevo, Nathalie, Smadja, David, M   +24 more
core   +1 more source

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

ESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen, Aldina Pivodic, Maria Schaufelberger, Annika Rosengren, Michael Fu   +4 more
wiley   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Insights into the use of biomarkers in calcific aortic valve disease [PDF]

, 2010
Calcific aortic valve disease (CAVD) is the most common acquired valvular disorder in developed countries. CAVD ranges from mild thickening of the valve, known as aortic valve sclerosis (AVSc), to severe impairment of the valve motion, which is termed ...
Grau J. B., Ferrari G., Sainger R., Beckmann E., Poggio P.   +4 more
core   +2 more sources

Calcific aortic stenosis: a disease of the valve and the myocardium.

Journal of the American College of Cardiology, 2013
Although aortic stenosis is a common condition associated with major morbidity, mortality, and health economic costs, there are currently no medical interventions capable of delaying or halting its progression. Re-evaluation of the underlying pathophysiology is therefore required so that novel therapeutic strategies can be developed. Aortic stenosis is
Dweck, Marc R., Boon, Nicholas A., Newby, David E.   +2 more
openaire   +2 more sources

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Editor’s Pick: Lipoprotein(a) and Calcific Aortic Valve Stenosis

European Medical Journal Cardiology, 2019
Calcific aortic valve stenosis is the most common valve disease in the elderly population and is associated with significant morbidity and mortality.
Constantine E. Kosmas, Delia Silverio, Andreas Sourlas, Frederick N. Campos, Peter D. Montan, Eliscer Guzman   +5 more
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