Results 101 to 110 of about 5,149,759 (252)

Age Differences in Aortic Stenosis

Reviews in Cardiovascular Medicine
Aortic stenosis (AS) is a significant and growing concern, with a prevalence of 2–3% in individuals aged over 65 years. Moreover, with an aging global population, the prevalence is anticipated to double by 2050.
Tomoyo Hamana, Teruo Sekimoto, Aloke V. Finn, Renu Virmani   +3 more
doaj   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Transcatheter implantation of a new prototype of self-expanding aortic valve prosthesis: first experience

Патология кровообращения и кардиохирургия, 2016
Calcific aortic stenosis is an aortic valve disease of atherosclerotic origin occurring in 2-4 % of persons older than 65 years, for whom open surgery is contraindicated. Models of self-expanding aortic valves available today have a number of significant
Е. И. Кретов, К. В. Козырь, А. Р. Таркова, Д. С. Сергеевичев, А. А. Коробейников, Т. П. Тимченко, Д. Д. Зубарев, И. С. Зыков, В. И. Байструков   +8 more
doaj   +1 more source

Table_1_Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells.docx

, 2021
Objectives: This study explores the concentration and role of glucagon-like peptide-1 (GLP-1) in calcific aortic valve disease (CAVD).Background: Calcific aortic valve disease is a chronic disease presenting with aortic valve degeneration and ...
Ying Yang (24175), Qihong Wu (438570), Ke Yang (192709), Fan Xiao (1422463), Zhongli Chen (9516953), Yan Liu (25061), Qing Zha (8998817), Qianru Zhang (292683)   +7 more
core   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Hypoxia Stimulates Synthesis of Neutrophil Gelatinase-Associated Lipocalin in Aortic Valve Disease

Frontiers in Cardiovascular Medicine, 2019
Objective: Aortic valve disease is commonly found in the elderly population. It is characterized by dysregulated extracellular matrix remodeling followed by extensive microcalcification of the aortic valve and activation of valve interstitial cells.
Ganesh Swaminathan, Varun K. Krishnamurthy, Swetha Sridhar, Denise C. Robson, Yao Ning, K. Jane Grande-Allen   +5 more
doaj   +1 more source

Calcific Aortic Valve Disease: Molecular Mechanisms and Therapeutic Approaches [PDF]

, 2015
Calcification occurs in atherosclerotic vascular lesions and in the aortic valve. Calcific aortic valve disease (CAVD) is a slow, progressive disorder that ranges from mild valve thickening without obstruction of blood flow, termed aortic sclerosis, to ...
Lerman, Daniel Alejandro, Lerman, Alejandro Daniel, Alotti, Nasri, Prasad, Sai   +3 more
core   +1 more source

Table_2_Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells.docx

, 2021
Objectives: This study explores the concentration and role of glucagon-like peptide-1 (GLP-1) in calcific aortic valve disease (CAVD).Background: Calcific aortic valve disease is a chronic disease presenting with aortic valve degeneration and ...
Ying Yang (24175), Qihong Wu (438570), Ke Yang (192709), Fan Xiao (1422463), Zhongli Chen (9516953), Yan Liu (25061), Qing Zha (8998817), Qianru Zhang (292683)   +7 more
core   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source