Results 81 to 90 of about 5,149,759 (252)

Use of Intracoronary Pressure Wire Assessment and Association With Outcomes: Insights From the British Cardiovascular Intervention Society National Database

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Despite recommendations in international guidelines, Intracoronary pressure wire assessment (PWA) utilization remains limited in clinical practice. This study aims to describe (i) trends of PWA during Percutaneous coronary interventional (PCI), (ii) factors that predict its application, and (iii) association with in‐hospital ...
Hussein Bashar, Muhammad Rashid, Mamas A. Mamas, Nick Curzen   +3 more
wiley   +1 more source

Differential expression of circulating markers of calcific aortic valve disease

, 2020
Differential protein expression of circulating markers of calcific aortic valve disease in healthy control vs aortic valve sclerosis patients, aortic valve sclerosis vs aortic stenosis patients, and healthy control vs aortic stenosis patients (Table S8).
Lisa Salvador (7517131), Aeron Small (7517125), Nancy Rioux (7517149), Robert Levy (7517153), Wanda Anselmo (7517122), Mary Ellen Cvijic (7517162), Melissa Yarde (7517147), Yichuan Liu (7517124), Juan Grau (7517123), Zhuyin Li (7517156), Giovanni Ferrari (7517159), Lei Zhao (7517141), Alex Kossar (7474772)   +12 more
core   +1 more source

Comparison Between the Acurate Neo and the Acurate Neo 2 Transcatheter Heart Valve System: Impact of Midframe Under‐Expansion

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter aortic valve implantation (TAVI) with the Acurate Neo has been linked to a significant incidence of paravalvular leakage (PVL), addressed by the Acurate Neo 2 incorporating an active sealing skirt. Recent findings suggest that midframe under‐expansion is associated with worse outcomes.
Lisa Crusius, Thaddäus Ast, Stephan Haussig, Jean‐Honoré Steul, Felix J. Woitek, Peter Sick, Tomas Madej, Utz Kappert, Axel Linke, Norman Mangner   +9 more
wiley   +1 more source

Innate and Adaptive Immunity in Calcific Aortic Valve Disease [PDF]

Journal of Immunology Research, 2015
Calcific aortic valve disease (CAVD) is the most common heart valve disorder. CAVD is a chronic process characterized by a pathologic mineralization of valve leaflets. Ectopic mineralization of the aortic valve involves complex relationships with immunity. Studies have highlighted that both innate and adaptive immunity play a role in the development of
Patrick Mathieu, Rihab Bouchareb, Marie-Chloé Boulanger   +2 more
openaire   +3 more sources

Feasibility and Procedural Considerations of Balloon‐Expandable TAVR in Patients With Prior Endovascular Aortic Stent Grafts

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Objectives To evaluate the feasibility and short‐term outcomes of transcatheter aortic valve replacement (TAVR) using balloon‐expandable Sapien valves in patients with prior endovascular aortic stent grafts. Methods We conducted a single‐center, retrospective study of 23 patients with prior endovascular aortic stent grafts who underwent TAVR ...
Iad Alhallak, Alexander Mills, Beau Bequeaith, Ken Chan, Akiko Tanaka, Anthony L. Estrera, Biswajit Kar, Richard Smalling, Abhijeet Dhoble   +8 more
wiley   +1 more source

FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease

Redox Biology
The prevalence of calcific aortic valve disease (CAVD) remains substantial while there is currently no medical therapy available. Forkhead box O1 (FOXO1) is known to be involved in the pathogenesis of cardiovascular diseases, including vascular ...
Chen Jiang, Dingyi Yao, Zongtao Liu, Yidan Zheng, Ming Chen, Wai Yen Yim, Qiang Zheng, Tailong Zhang, Lin Fan, Zhengfeng Fan, Bingchuan Geng, Rui Tian, Tingwen Zhou, Weihua Qiao, Jiawei Shi, Fei Li, Li Xu, Yuming Huang, Nianguo Dong   +18 more
doaj   +1 more source

Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model.

PLoS ONE, 2020
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism.
J Ethan Joll, Cynthia R Clark, Christine S Peters, Michael A Raddatz, Matthew R Bersi, W David Merryman   +5 more
doaj   +1 more source

Lipoprotein(a) and Body Mass Compound the Risk of Calcific Aortic Valve Disease

, 2022
Background: High plasma lipoprotein(a) and high body mass index are both causal risk factors for calcific aortic valve disease. Objectives: This study sought to test the hypothesis that risk of calcific aortic valve disease is the highest when both ...
Nordestgaard, Børge G., Afzal, Shoaib, Langsted, Anne, Kaltoft, Morten, Kamstrup, Pia R.   +4 more
core   +1 more source

Gutter Rotation Technique for Percutaneous Ipsilateral Retrieval of a Ruptured SAPIEN‐3 Balloon

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Balloon rupture during transcatheter aortic valve replacement (TAVR) with balloon‐expandable valves is a rare but potentially serious complication that may result in incomplete valve expansion, difficult device retrieval, and vascular injury.
Anne Venkata Ganeshkumar, Guru Chaithanya Kumar Chagalakondu, Naveen Kumar Murki, Siva Sankara Kattinti, Sarat Surapaneni, Somaraju Bhupatiraju   +5 more
wiley   +1 more source

Potential drug targets for calcific aortic valve disease [PDF]

Nature Reviews Cardiology, 2014
Calcific aortic valve disease (CAVD) is a major contributor to cardiovascular morbidity and mortality and, given its association with age, the prevalence of CAVD is expected to continue to rise as global life expectancy increases. No drug strategies currently exist to prevent or treat CAVD.
Joshua D, Hutcheson, Elena, Aikawa, W David, Merryman   +2 more
openaire   +2 more sources