Results 61 to 70 of about 5,149,759 (252)

Local versus general anesthesia for transcatheter aortic valve implantation (TAVR)- systematic review and meta-analysis [PDF]

, 2014
The hypothesis of this study was that local anesthesia with monitored anesthesia care (MAC) is not harmful in comparison to general anesthesia (GA) for patients undergoing Transcatheter Aortic Valve Implantation (TAVR).TAVR is a rapidly spreading ...
Webb, J, Reinthaler, M, Georg M Fröhlich, Marco Roffi, Olaf Wendler, Nevil Hutchinson, Markus Reinthaler, Duolao Wang, David Hildick-Smith, Wang, D, Hutchinson, N, Fröhlich, GM, John Webb, Pascal Meier, Alexandra J Lansky, Wendler, O, Hildick-Smith, D, Stefan Toggweiler, Lansky, AJ, Roffi, M, Meier, P, Toggweiler, S   +21 more
core   +2 more sources

Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease [PDF]

British Journal of Pharmacology, 2019
Background and PurposeCalcification of heart valves is a frequent pathological finding in chronic kidney disease and in elderly patients. Hydrogen sulfide (H2S) may exert anti‐calcific actions. Here we investigated H2S as an inhibitor of valvular calcification and to identify its targets in the pathogenesis.Experimental ApproachEffects of H2S on ...
Katalin Éva Sikura, László Potor, Tamás Szerafin, Melinda Oros, Péter Nagy, Gábor Méhes, Zoltán Hendrik, Abolfazl Zarjou, Anupam Agarwal, Niké Posta, Roberta Torregrossa, Matthew Whiteman, Ibolya Fürtös, György Balla, József Balla   +14 more
openaire   +3 more sources

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

Cross Talk between NOTCH Signaling and Biomechanics in Human Aortic Valve Disease Pathogenesis

Journal of Cardiovascular Development and Disease, 2014
Aortic valve disease is a burgeoning public health problem associated with significant mortality. Loss of function mutations in NOTCH1 cause bicuspid aortic valve (BAV) and calcific aortic valve disease.
Richard C. Godby, Charu Munjal, Amy M. Opoka, J. Michael Smith, Katherine E. Yutzey, Daria A. Narmoneva, Robert B. Hinton   +6 more
doaj   +1 more source

Cholesterol efflux promoting function of high-density lipoproteins in calcific aortic valve stenosis

Atherosclerosis Plus, 2021
Background and aims: Cholesterol efflux capacity is a functional property of high-density lipoproteins (HDL) reflecting the efficiency of the atheroprotective reverse cholesterol transport process in humans.
Duygu Kocyigit, Francesca Zimetti, Kadri M. Gurses, Ilaria Zanotti, Cinzia Marchi, Marcus Ståhlman, Jan Borén, Hande Canpinar, Mehmet F.T. Soyal, Dicle Guc, Tuncay Hazirolan, Necla Ozer, Lale Tokgozoglu   +12 more
doaj   +1 more source

Spectrum of Calcific Aortic Valve Disease [PDF]

Circulation, 2005
Received October 26, 2004; revision received January 13, 2005; accepted February 4, 2005. Calcific aortic valve disease is a slowly progressive disorder with a disease continuum that ranges from mild valve thickening without obstruction of blood flow, termed aortic sclerosis, to severe calcification with impaired leaflet motion, or aortic stenosis ...
Rosario V, Freeman, Catherine M, Otto
openaire   +2 more sources

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

The ‘valvulo-metabolic’ risk in calcific aortic valve disease [PDF]

Canadian Journal of Cardiology, 2007
Calcific aortic stenosis (AS) has been considered a degenerative and unmodifiable process resulting from aging and 'wear and tear' of the aortic valve. Over the past decade, studies in the field of epidemiology, molecular biology and lipid metabolism have highlighted similarities between vascular atherosclerosis and calcific AS.
Patrick, Mathieu, J P, Després, P, Pibarot   +2 more
openaire   +2 more sources

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

3DTEE as an alternative approach for the evaluation of aortic valve complex in CKD post renal transplant patient for transcatheter aortic valve implantation (TAVI)

IHJ Cardiovascular Case Reports, 2021
Transcatheter aortic valve implantation (TAVI) is an innovative and less invasive treatment for most of the population with severe aortic stenosis (AS).
Hemant Chaturvedi, Ravindra Singh Rao
doaj   +1 more source