Results 41 to 50 of about 5,149,759 (252)

Upregulation of Cartilage Oligomeric Matrix Protein and Bone Morphogenetic Protein-2 May Associate with Calcific Aortic Valve Disease

Cardiology Discovery, 2021
. Objective:. Calcific aortic valve disease (CAVD) affects millions of elderly people, and there is currently no effective way to stop or slow down its progression.
Yueyue Xu, Yide Cao, Yafeng Liu, Jingsong Wang, Ganyi Chen, Zhonghao Tao, Yiwei Yao, Yuchen Cai, Yunzhang Wu, Wen Chen, Tianyu Xu, Xiaoxia Fu   +11 more
doaj   +1 more source

Aortic valve calcification in chronic kidney disease [PDF]

Nephrology Dialysis Transplantation, 2013
Several clinical studies reported an increased prevalence and accelerated progression of aortic valve calcification among patients with end-stage renal disease when compared with subjects with normal kidney function. Recently, mechanisms of calcific valve degeneration have been further elucidated and many of the pathways involved could be amplified in ...
RATTAZZI, MARCELLO, E. Bertacco, A. Del Vecchio, M. Puato, FAGGIN, ELISABETTA, PAULETTO, PAOLO   +5 more
openaire   +4 more sources

Transcatheter versus surgical aortic-valve replacement in high-risk patients. [PDF]

, 2011
BACKGROUND: The use of transcatheter aortic-valve replacement has been shown to reduce mortality among high-risk patients with aortic stenosis who are not candidates for surgical replacement.
Makkar, Raj R, Samir Kapadia, Dewey, Todd, Pichard, Augusto D, Mack, Michael J, Vinod H. Thourani, Duolao Wang, Smith, Craig R, Webb, John G, Babaliaros, Vasilis, Moses, Jeffrey W, D. Craig Miller, Jeffrey W. Moses, Wang, Duolao, Craig R. Smith, Mathew Williams, Todd Dewey, Miller, D Craig, Michael J. Mack, John G. Webb, William N. Anderson, Tuzcu, E Murat, Thourani, Vinod H, Raj R. Makkar, Gregory P. Fontana, Svensson, Lars G, Kapadia, Samir, E. Murat Tuzcu, Paul Corso, Martin B. Leon, Williams, Mathew, Stuart J. Pocock, Bavaria, Joseph E, MD, Howard C. Herrmann, Augusto D. Pichard, Lars G. Svensson, Pocock, Stuart J, Jodi J. Akin, Joseph E. Bavaria, Fontana, Gregory P, Akin, Jodi J, Corso, Paul, Bavaria, Joseph E, Leon, Martin B, Herrmann, Howard C, PARTNER Trial Investigators, Anderson, William N, Vasilis Babaliaros   +47 more
core   +1 more source

Diabetes and calcific aortic valve disease: controversy of clinical outcomes in diabetes after aortic valve replacement [PDF]

Frontiers in Endocrinology
Haipeng Cai
exaly   +2 more sources

Health Behaviors and Calcific Aortic Valve Disease [PDF]

Journal of the American Heart Association, 2018
Calcific aortic valve disease (CAVD) is the most common form of valvular heart disease worldwide and is associated with increased mortality across the spectrum of severity of disease.[1][1] The 1‐year mortality rates among individuals with untreated severe symptomatic aortic stenosis nears 50 ...
Julio A. Lamprea‐Montealegre, Catherine M. Otto   +1 more
openaire   +3 more sources

Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression

Molecular Medicine, 2023
Background Calcific aortic valve disease (CAVD) is the second leading cause of adult heart diseases. The purpose of this study is to investigate whether miR-101-3p plays a role in the human aortic valve interstitial cells (HAVICs) calcification and the ...
Jianglei Chen, Yi Lin, Zhongjie Sun
doaj   +1 more source

Role of follistatin-like 1 levels and functions in calcific aortic stenosis

Frontiers in Cardiovascular Medicine, 2023
BackgroundCalcific aortic valve disease (CAVD) is a progressive disease resulting in severe calcific aortic stenosis (AS), and there is increasing interest in the discovery of novel biomarkers to identify patients with potential future calcific AS at an ...
Qianru Zhang, Jiawen Ye, Gan Yang, Ling Yang, Zhongli Chen, Ke Yang, Jia Teng Sun, Yan Liu   +7 more
doaj   +1 more source

Molecular imaging of calcific aortic valve disease [PDF]

Journal of Nuclear Cardiology, 2018
Calcific aortic valve disease (CAVD) can progress to symptomatic aortic stenosis in a subset of patients. The severity of aortic stenosis and the extent of valvular calcification can be evaluated readily by echocardiography, CT, and MRI using well-established imaging protocols. However, these techniques fail to address optimally other important aspects
Jae-Joon, Jung, Farid, Jadbabaie, Mehran M, Sadeghi   +2 more
openaire   +2 more sources

Aortic Valve Sclerosis and Degenerative Valve Disease in a Nigerian Population: An Echocardiographic Study

Global Heart
Background: The burden of degenerative valve disease is increasing globally because of population aging. However, data on this condition is scarce in Nigeria and across Africa.
Olugbenga O. Abiodun, Ibrahim L. Salau, Tina Anya   +2 more
doaj   +1 more source

Lipoprotein(a) Gene Polymorphism Increases a Risk Factor for Aortic Valve Calcification

Journal of Cardiovascular Development and Disease, 2019
Calcific aortic valve disease (CAVD) is a multifactorial condition. Both environmental and genetic factors play an important role in its etiology. CAVD exhibits a broad spectrum, varying from mild valve thickening to severe valve calcification and ...
Ugur Ozkan, Fatih Ozcelik, Mustafa Yildiz, Metin Budak   +3 more
doaj   +1 more source