Results 91 to 100 of about 19,695 (283)

Central role of pyrophosphate in acellular cementum formation.

PLoS ONE, 2012
BackgroundInorganic pyrophosphate (PP(i)) is a physiologic inhibitor of hydroxyapatite mineral precipitation involved in regulating mineralized tissue development and pathologic calcification.
Brian L Foster, Kanako J Nagatomo, Francisco H Nociti, Hanson Fong, Daisy Dunn, Anne B Tran, Wei Wang, Sonoko Narisawa, Jose Luis Millán, Martha J Somerman   +9 more
doaj   +1 more source

Primary familial brain calcification linked to deletion of 5' noncoding region of SLC20A2 [PDF]

, 2017
OBJECTIVES: Primary familial brain calcification (PFBC) is a rare neurological disease often inherited as a dominant trait. Mutations in four genes (SLC20A2, PDGFB, PDGFRB, and XPR1) have been reported in patients with PFBC.
Baumann, M, Baumann, P, Bras, J, Guerreiro, R, Myllykangas, L, Mäkinen, J, Pasanen, P, Pöyhönen, M, Tienari, PJ, Valori, M, Viitanen, M   +10 more
core  

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J, Chu, Mon-Li, Halabi, Carmen M, Lee, Vivian S, Lin, Michelle, Mecham, Robert P   +5 more
core   +3 more sources

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

Arthritis Care &Research, EarlyView.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech, Charles G. Frech, W. David Merryman, Andrew Sternlicht, Justin Baba   +4 more
wiley   +1 more source

Avaliação do efeito do ibandronato na consolidação de fratura: estudo experimental em coelhos Evaluation of ibandronate effects in bone healing: experimental study in rabbits

Revista Brasileira de Ortopedia, 2007
OBJETIVO: Determinar a presença de efeito favorável do ibandronato de sódio na consolidação óssea, contribuindo assim para estudos futuros visando sua utilização terapêutica no tratamento de fraturas e pseudartroses.
Roberto Guarniero, Carlos Eduardo Sanches Vaz, Paulo José de Santana, Éden Dal Molin, Juliana Braun, Marcel Shudi Harada   +5 more
doaj   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Thoracic calcifications on magnetic resonance imaging: correlations with computed tomography

Jornal Brasileiro de Pneumologia
Objective: To identify the characteristics of thoracic calcifications on magnetic resonance (MR) imaging, as well as correlations between MR imaging and CT findings.
Juliana Fischman Zampieri, Gabriel Sartori Pacini, Matheus Zanon, Stephan Philip Leonhardt Altmayer, Guilherme Watte, Marcelo Barros, Evandra Durayski, Gustavo de Souza Portes Meirelles, Marcos Duarte Guimarães, Edson Marchiori, Arthur Soares Souza Junior, Bruno Hochhegger   +11 more
doaj   +1 more source

Hematologic effects of placental pathology on very low birthweight infants born to mothers with preeclampsia. [PDF]

, 2009
OBJECTIVE: To investigate the effect of placental pathology on neonatal neutrophils, platelets, hematocrit and nucleated red blood cells in very low birthweight (VLBW) infants born to mothers with preeclampsia. STUDY DESIGN: Retrospective cohort study of
Kern, Jennifer, Mackley, RNC, Amy B, Paul. MD, David A, Zook, MD, Kelly J   +3 more
core   +1 more source

Association of urinary uromodulin with kidney function decline and mortality: the health ABC study
. [PDF]

, 2017
BackgroundUrine uromodulin (uUMOD) is a protein secreted by the kidney tubule. Recent studies have suggested that higher uUMOD may be associated with improved kidney and mortality outcomes.MethodsUsing a case-cohort design, we evaluated the association ...
Bennett, Michael R, Devarajan, Prasad, Fried, Linda F, Garimella, Pranav S, Gutiérrez, Orlando M, Harris, Tamara B, Ix, Joachim H, Katz, Ronit, Kritchevsky, Stephen B, Parikh, Chirag R, Sarnak, Mark J, Shlipak, Michael G   +11 more
core   +1 more source