Results 71 to 80 of about 531,192 (386)

Calculating the global contribution of coralline algae to carbon burial [PDF]

open access: yes, 2015
The ongoing increase in anthropogenic carbon dioxide (CO2) emissions is changing the global marine environment and is causing warming and acidification of the oceans.
Kamenos, N. A., van der Heijden, L. H.
core   +1 more source

The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification

open access: yesJournal of Diabetes Research, 2016
AGE/RAGE signaling has been a well-studied cascade in many different disease states, particularly diabetes. Due to the complex nature of the receptor and multiple intersecting pathways, the AGE/RAGE signaling mechanism is still not well understood.
Amber M. Kay, C. L. Simpson, J. Stewart
semanticscholar   +1 more source

Mitochondrial Calcification

open access: yesImmunometabolism, 2021
Abstract One of the most fascinating aspects of mitochondria is their remarkable ability to accumulate and store large amounts of calcium in the presence of phosphate leading to mitochondrial calcification. In this paper, we briefly address the mechanisms that regulate mitochondrial calcium homeostasis followed by the extensive
Duvvuri, Bhargavi, Lood, Christian
openaire   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Comparative Sensitivities of Zooplankton to Ocean Acidification Conditions in Experimental and Natural Settings

open access: yesFrontiers in Marine Science, 2021
Zooplankton can serve as indicators of ecosystem health, water quality, food web structure, and environmental change, including those associated with climate change and ocean acidification (OA).
Katherine E. Keil   +5 more
doaj   +1 more source

No compromise between metabolism and behavior of decorator crabs in reduced pH conditions. [PDF]

open access: yes, 2019
Many marine calcifiers experience metabolic costs when exposed to experimental ocean acidification conditions, potentially limiting the energy available to support regulatory processes and behaviors. Decorator crabs expend energy on decoration camouflage
Graeve, Olivia A   +3 more
core   +3 more sources

Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet

open access: yesFrontiers in Cardiovascular Medicine, 2019
The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed light on the consequences of loss-of-function mutations for different ...
Magnus Bäck   +17 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Local inflammatory response to suture material in surgical practice: experimental data

open access: yesВестник трансплантологии и искусственных органов, 2020
Objective: to study the effect of various types of suture materials, potentially suitable for cardiovascular surgery, on experimental surgical outcomes. Materials and methods.
T. N. Akentyeva   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy