Results 71 to 80 of about 508,286 (387)
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Circulating microRNAs and vascular calcification in hemodialysis patients
Journal of International Medical Research, 2019 Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated.
Chien-Te Lee +4 more
doaj +1 more source
Cerebral Microbleeds in a Stroke Prevention Clinic. [PDF]
, 2019 The objective of this study is to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January ...
Chang, Peter +7 more
core +1 more source
Journal of the American Society of Nephrology, 2018 Background The high cardiovascular morbidity and mortality of patients with CKD may result in large part from medial vascular calcification, a process promoted by hyperphosphatemia and involving osteo-/chondrogenic transdifferentiation of vascular smooth
J. Voelkl +16 more
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Vascular Leiomyoma of Foot [PDF]
Journal of Clinical and Diagnostic Research, 2013 Vascular leiomyomas of the foot are relatively rare benign soft tissue tumours which arise from the tunica media and present as painful or painless solitary subcutaneous nodules.
Suhith Gajanthodi +2 more
doaj +1 more source
Exercise and Coronary Atherosclerosis: Observations, Explanations, Relevance, and Clinical Management. [PDF]
, 2020 Physical activity and exercise training are effective strategies for reducing the risk of cardiovascular events, but multiple studies have reported an increased prevalence of coronary atherosclerosis, usually measured as coronary artery calcification ...
Aengevaeren, VL +7 more
core +3 more sources
The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification
Journal of Diabetes Research, 2016 AGE/RAGE signaling has been a well-studied cascade in many different disease states, particularly diabetes. Due to the complex nature of the receptor and multiple intersecting pathways, the AGE/RAGE signaling mechanism is still not well understood.
Amber M. Kay, C. L. Simpson, J. Stewart
semanticscholar +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
SGK1 induces vascular smooth muscle cell calcification through NF‐&kgr;B signaling
Journal of Clinical Investigation, 2018 &NA; Medial vascular calcification, associated with enhanced mortality in chronic kidney disease (CKD), is fostered by osteo‐/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs).
J. Voelkl +17 more
semanticscholar +1 more source