Results 81 to 90 of about 333,706 (363)

Calcification depth of deep-dwelling planktonic foraminifera from the eastern North Atlantic constrained by stable oxygen isotope ratios of shells from stratified plankton tows [PDF]

open access: yes, 2019
Stable oxygen isotopes (delta O-18) of planktonic foraminifera are one of the most used tools to reconstruct environmental conditions of the water column. Since different species live and calcify at different depths in the water column, the delta O-18 of
Jonkers, Lukas   +5 more
core   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Sinomenine attenuates uremia vascular calcification by miR-143-5p

open access: yesScientific Reports
Vascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu   +10 more
doaj   +1 more source

Correlation of hs-CRP, NLR and PLR tocardiac valve calcification in maintenance hemodialysis patients

open access: yesLinchuang shenzangbing zazhi, 2020
Objective To investigate the levels of hypersensitivity C-reaction protein(hs-CRP), neutrophil/lymphocyte ratio(NLR) and platelet lymphocyte ratio(PLR) in patients with maintenance hemodialysis(MHD), and to analyze their correlation with cardiac valve ...
WANG Yun-dan, JIANG Wei-jie
doaj  

Frequency of abdominal aortic calcification in a group of Iraqi hemodialysis patients

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2014
Cardiovascular complications including abdominal aortic calcification significantly affect the mortality and morbidity in patients on a hemodialysis (HD) program.
Ali J Hashim Al-Saedi   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Seagrass can mitigate negative ocean acidification effects on calcifying algae [PDF]

open access: yes, 2019
The ultimate effect that ocean acidification (OA) and warming will have on the physiology of calcifying algae is still largely uncertain. Responses depend on the complex interactions between seawater chemistry, global/local stressors and species-specific
A Buosi   +61 more
core   +2 more sources

On the Mechanisms of Calcification.

open access: yesExperimental Biology and Medicine, 1958
SummarySpecimens of skin, tendon, and cortical bone from the calf were exhaustively demineralized with EDTA at pH 7.4. These tissues were then equilibrated with solutions of varying calcium and phosphorus content. All 3 tissues, presumably because of their collagen content, were able to induce formation of hydroxy apatite crystals from otherwise stable
Basil Strates, William F. Neuman
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Characteristics and prognostic values of abdominal aortic branches calcification in hemodialysis patients

open access: yesRenal Failure
Background Vascular calcification is highly prevalent and associated with mortality in hemodialysis patients. However, extreme splanchnic arterial calcification in calciphylaxis with poor prognosis raises questions regarding the reliability of previous ...
Wen Shi   +4 more
doaj   +1 more source

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