Calcitonin gene-related peptide causes migraine aura
The Journal of Headache and Pain, 2023 Background Although the involvement of calcitonin gene-related peptide (CGRP) in migraines is well-established, its specific role in investigating the aura phase, which often precedes the headache, remains largely unexplored. This study aims to instigate
Haidar M. Al-Khazali +8 more
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Calcitonin gene-related peptide [PDF]
Drugs & Aging, 1993 Stief, Christian Georg +5 more
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RETRACTED: Mancinelli et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells 2022, 11, 1591 [PDF]
CellsThe journal retracts the article titled “The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling” [...]
Romina Mancinelli +17 more
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Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide [PDF]
Communications MedicineBackground The success of passive immunotherapies targeting Calcitonin gene-related peptide (CGRP) for managing migraine has prompted our efforts towards developing an active immunotherapy that induces the production of endogenous antibodies against CGRP.
Justin D. Boyd +15 more
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Heat hyperalgesia and mechanical hypersensitivity induced by calcitonin gene-related peptide in a mouse model of neurofibromatosis. [PDF]
PLoS ONE, 2014 This study examined whether mice with a deficiency of neurofibromin, a Ras GTPase activating protein, exhibit a nociceptive phenotype and probed a possible contribution by calcitonin gene-related peptide.
Stephanie White +3 more
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Improved osteoarthritis during erenumab treatment for migraine: a case report
Case Reports in Neurology, 2023 Antibodies blocking the calcitonin gene-related peptide have revolutionized episodic and chronic migraine treatment. However, their applicability to non-cephalic pain conditions, such as osteoarthritis is yet unknown.
Frederik Thal Jantzen +3 more
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Correlation between CGRP Levels and the Neuropathic and Inflammatory Component of Postoperative Pain [PDF]
Folia Medica, 2020 Introduction: In surgical procedures, tissue damage results in the release of a number of bioactive substances. Calcitonin gene-related peptide (CGRP) is a peptide released from sensory nerves, which determines its role in pain sensation.
Deyan Neychev +5 more
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Calcitonin Gene-Related Peptide in Charcot Foot Neuroarthropathy
Foot & Ankle Orthopaedics, 2022 Category: Basic Sciences/Biologics; Diabetes Introduction/Purpose: Charcot neuroarthropathy (CNA) is a destructive joint condition secondary to neuropathic deficiency.
Yi Guo +5 more
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The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes
Frontiers in Endocrinology, 2018 Calcitonin (CT)/CT gene-related peptide (CGRP) family peptides (CT/CGRP family peptides) including CT, CGRP, adrenomedullin, amylin, and CT receptor-stimulating peptide have been identified from various vertebrates and perform a variety of important ...
Toshio Sekiguchi
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Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors
Frontiers in Molecular Biosciences, 2021 Class B1 G protein-coupled receptors (GPCRs) are important targets for many diseases, including cancer, diabetes, and heart disease. All the approved drugs for this receptor family are peptides that mimic the endogenous activating hormones.
Giuseppe Deganutti +7 more
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