Results 41 to 50 of about 97,221 (328)

Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. [PDF]

, 2017
BACKGROUND: Frequent mild head injuries or concussion along with the presence of headache may contribute to the persistence of concussion symptoms. METHODS: In this study, the acute effects of recovery between mild head injuries and the frequency of ...
Assari, Soroush, Cheng, Lan, Darvish, Kurosh, Elliott, Melanie B, Tyburski, Ashley L.   +4 more
core   +2 more sources

Is Helicobacter Pylori Associated with a Migraine? [PDF]

, 2017
Objective: To determine whether Helicobacter pylori (H. pylori) is associated with migraine headache. Design: Case-control study. Settings: Local tertiary Hospitals in Cairo, Egypt and in HaferAlbaten, Saudi Arabia.
Ali Radwa A, Mahmoud Mohamed A, Ali Abdelrazak M   +2 more
core   +1 more source

Calcitonin gene‐related peptide‐targeting therapies are a first‐line option for the prevention of migraine: An American Headache Society position statement update

Headache
To provide a position statement update from The American Headache Society specifically regarding therapies targeting calcitonin gene‐related peptide (CGRP) for the prevention of migraine.
Andrew C Charles, Kathleen B. Digre, P. Goadsby, Matthew S. Robbins, Andrew D. Hershey   +4 more
semanticscholar   +1 more source

Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest [PDF]

, 2018
Hylobius abietis (Linnaeus), or large pine weevil (Coleoptera, Curculionidae), is a pest of European coniferous forests. In order to gain understanding of the functional physiology of this species, we have assembled a de novo transcriptome of H. abietis,
Davies, Shireen-Anne, Dow, Julian A.T., Inward, Daegan J.G., Marley, Richard, Pandit, Aniruddha A., Predel, Reinhard, Ragionieri, Lapo, Yeoh, Joseph G.C.   +7 more
core   +1 more source

Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models

Journal of Neuroscience, 2019
Migraine is the second leading cause for disability worldwide and the most common neurological disorder. It is also three times more common in women; reasons for this sex difference are not known.
Amanda Avona, C. Burgos-Vega, M. Burton, A. Akopian, Theodore John Price, G. Dussor   +5 more
semanticscholar   +1 more source

Treating Menière’s disease with rimegepant

Swiss Medical Weekly
A recent hypothesis states that Menière’s disease is caused by inappropriate expression, i.e. enhanced release of the neurotransmitter calcitonin gene-related peptide.
Stefan C. A. Hegemann, Angela Schell
doaj   +1 more source

Reducing Episodic Cluster Headaches: Focus on Galcanezumab

Journal of Pain Research, 2020
Lanfranco Pellesi,1 Roberto De Icco,2,3 Mohammad Al-Mahdi Al-Karagholi,1 Messoud Ashina1,4 1Danish Headache Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; 2Headache Science Center, IRCCS Mondino Foundation,
Pellesi L, De Icco R, Al-Karagholi MA, Ashina M   +3 more
doaj  

Research Progress in Calcitonin Gene-Related Peptide and Bone Repair

Biomolecules, 2023
Calcitonin gene-related peptide (CGRP) has 37 amino acids. Initially, CGRP had vasodilatory and nociceptive effects. As research progressed, evidence revealed that the peripheral nervous system is closely associated with bone metabolism, osteogenesis ...
Qichang Wang, Haotian Qin, Jiapeng Deng, Huihui Xu, Su Liu, Jian Weng, Hui Zeng   +6 more
doaj   +1 more source

Calcitonin gene-related peptide is a key neurotransmitter in the neuro-immune axis [PDF]

, 2014
The question of how the neural and immune systems interact in host defence is important, integrating a system that senses the whole body with one that protects.
Bakri M. Assas, Jaleel A. Miyan, Joanne I. Pennock   +2 more
core   +2 more sources

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source