Results 71 to 80 of about 97,221 (328)

Calcitonin gene-related peptide regulates periodontal tissue regeneration

Scientific Reports
Calcitonin gene-related peptide (CGRP), a neuropeptide composed of 37 amino acids secreted from the sensory nerve endings, reportedly possesses various physiological effects, such as vasodilation and neurotransmission.
Koji Miki, Noboru Takeshita, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami   +4 more
doaj   +1 more source

Periosteum Metabolism and Nerve Fiber Positioning Depend on Interactions between Osteoblasts and Peripheral Innervation in Rat Mandible. [PDF]

PLoS ONE, 2015
The sympathetic nervous system controls bone remodeling by regulating bone formation and resorption. How nerves and bone cells influence each other remains elusive.
Cédric Mauprivez, Caroline Bataille, Brigitte Baroukh, Annie Llorens, Julie Lesieur, Pierre J Marie, Jean-Louis Saffar, Martin Biosse Duplan, Marc Cherruau   +8 more
doaj   +1 more source

Erenumab is effective in reducing migraine frequency and improving physical functioning [PDF]

, 2018
no abstract ...
Martelletti, Paolo
core   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Calcitonin-gene related peptide and disease activity in cluster headache

Cephalalgia, 2019
Objective To investigate the role of calcitonin gene-related peptide, pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide in cluster headache, we measured these vasoactive peptides interictally and during
A. Snoer, A. L. Vollesen, Rasmus P Beske, Song Guo, Jan Hoffmann, Jan Fahrenkrug, N. R. Jørgensen, T. Martinussen, R. Jensen, M. Ashina   +9 more
semanticscholar   +1 more source

Impaired wound healing in a migraine patient as a possible side effect of calcitonin gene-related peptide receptor antibody treatment: A case report

Cephalalgia, 2020
Introduction Wound healing disturbances as possible side effects of calcitonin gene-related peptide (CGRP) antibody treatment have been discussed previously but not yet described in humans.
S. Wurthmann, S. Nägel, E. Hadaschik, Swantje Schlott, A. Scheffler, C. Kleinschnitz, D. Holle   +6 more
semanticscholar   +1 more source

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source

CGRP Receptor Family and Accessory Protein Localization: Implications for Predicted Function

The Scientific World Journal, 2001
Calcitonin gene-related peptide (CGRP), adrenomedullin, amylin, and calcitonin are functionally related neuropeptides. Certain of these peptides mediate their action through receptors which have common components, such as the receptor activity modifying ...
K.R. Oliver
doaj   +1 more source

Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells

Respiratory Research, 2009
Background Alveolar epithelial cells are known as progenitor cells for the restoration from the damage in the lung. Calcitonin gene-related peptide (CGRP) has been reported to play an important role in the proliferation of various types of epithelial and
Yatera Kazuhiro, Asonuma Etsuko, Kido Takashi, Machida Kazuhiko, Nakamura Takehiro, Kim Heungnam, Morimoto Yasuo, Kawanami Yukiko, Yoshii Chiharu, Kido Masamitsu   +9 more
doaj   +1 more source

Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro [PDF]

, 2011
We examined roles of calcitonin family peptides in the initial stages of dendrite formation and the maturation of dendritic spines in the rat cerebral cortex in vitro.
Harigai Yuichi, Li Fei, Natsume Masaki, Ohtani Akiko, Senzaki Kouji, Shiga Takashi, 先崎 浩次, 志賀 隆   +7 more
core   +1 more source