Results 21 to 30 of about 49,400 (296)
Molecular Oncology, 2022 Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcitriol,
Katia Danza +8 more
doaj +1 more source
BMC Gastroenterology, 2020 Background Hypercalcemia of malignancy is not uncommon in patients with advanced stage cancer. In rare cases the cause of the hypercalcemia is excessive production of calcitriol, the active form of vitamin D.
Maarten Haemels +5 more
doaj +1 more source
Novel Insights into the Cardioprotective Effects of Calcitriol in Myocardial Infarction
Cells, 2022 Background: Increasing evidence indicates that vitamin D deficiency negatively affects the cardiovascular system. Here we studied the therapeutic effects of calcitriol in myocardial infarction (MI) and investigated its underlying mechanisms.
Simin Yang +12 more
doaj +1 more source
“Calcitriol” Is Not Synonymous with “Vitamin D” [PDF]
Multiple Sclerosis International, 2012 Regarding the recent article by Shaygannejad et al. [1], we are writing to express serious concerns about the portrayal of the intervention and the authors' interpretation and discussion of the findings. Of predominate concern is that the authors utilized a calcitriol intervention in their study but referred to it as “vitamin D”.
Kimball, Samantha M. +1 more
openaire +4 more sources
Frontiers in Endocrinology, 2023 Type 2 diabetes mellitus (T2DM)-associated periodontitis is a common disease with high prevalence, associated with persistent infection and complicated manifestations.
Yanan Wang +5 more
doaj +1 more source
Analysis of the interaction of calcitriol with the disulfide isomerase ERp57 [PDF]
, 2016 Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the ...
Altieri, Fabio +7 more
core +1 more source
Biomedicines, 2020 Initially, patients that respond to cisplatin (DDP) treatment later relapse and develop chemoresistance. Agents that enhance DDP effectiveness will have a significant impact on cancer treatment.
Ana Paucarmayta +6 more
doaj +1 more source
A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle [PDF]
, 2011 Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Martin-Tereso Lopez, J. +1 more
core +2 more sources
Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy. [PDF]
PLoS ONE, 2012 Calcitriol antiproliferative effects include inhibition of the oncogenic ether-à-go-go-1 potassium channel (Eag1) expression, which is necessary for cell cycle progression and tumorigenesis.
Janice García-Quiroz +13 more
doaj +1 more source
Journal of Immunology Research, 2021 Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE.
Mónica R. Meza-Meza +9 more
doaj +1 more source