Lymphoma and hypercalcemia in a pediatric orthotopic liver transplant patient [PDF]
, 1989 We present a case report of a pediatric orthotopic liver transplant recipient who developed lymphoma with hypercalcemia on cyclosporine and prednisone immunosuppression.
Esquivel, CO +6 more
core +1 more source
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent [PDF]
, 2016 BACKGROUND: Sarcoidosis is a multi-system disease characterized by the presence of non-caseating epithelioid granulomas in affected tissues, including skeletal muscle.
Eutsler, Eric Eutsler +4 more
core +2 more sources
Calcitriol Inhibits Viability and Proliferation in Human Malignant Pleural Mesothelioma Cells
Frontiers in Endocrinology, 2020 Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor, often associated with exposure to asbestos and characterized by poor prognosis and limited treatment options.
Iacopo Gesmundo +11 more
doaj +1 more source
Therapeutic effects of vitamin D on acetic acid-induced colitis in rats [PDF]
Acta Cirúrgica Brasileira, 2020 Purpose To analyze the effect of calcitriol treatment on acute colitis in an experimental rat model. Methods A total of 24 adult Sprague Dawley albino rats were randomly separated into 3 equal groups: control group (n:8), colitis group (n:8 ...
Refik Bademci +4 more
doaj +1 more source
Calcitriol suppression of parathyroid hormone fails to improve skeletal properties in an animal model of chronic kidney disease [PDF]
, 2016 BACKGROUND: Chronic kidney disease (CKD) leads to complex metabolic changes and an increased risk of fracture. Currently, calcitriol is the standard of care as it effectively suppresses parathyroid hormone (PTH) levels in CKD patients.
Allen, Matthew R. +7 more
core +1 more source
Leukemia Research Reports, 2018 In acute lymphoblastic leukemia (ALL), steroid resistance and hypovitaminosis D are both associated with a poor prognosis. We show that methylprednisolone, calcitriol and the AKT-inhibitor MK-2206 have a synergistic effect on the apoptosis of steroid ...
Maximilian Pistor +6 more
doaj +1 more source
Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]
, 2017 The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover +6 more
core +2 more sources
Bioconversion of vitamin D3 to bioactive calcifediol and calcitriol as high-value compounds
Biotechnology for Biofuels and Bioproducts, 2022 Biological catalysis is an important approach for the production of high-value-added compounds, especially for products with complex structures. Limited by the complex steps of chemical synthesis and low yields, the bioconversion of vitamin D3 (VD3) to ...
Zheyi Wang +6 more
doaj +1 more source
Exponentially Increasing Incidences of Cutaneous Malignant Melanoma in Europe Correlate with Low Personal Annual UV Doses and Suggests 2 Major Risk Factors [PDF]
, 2015 For several decades the incidence of cutaneous malignant melanoma (CMM) steadily increased in fair-skinned, indoor-working people around the world. Scientists think poor tanning ability resulting in sunburns initiate CMM, but they do not understand why ...
Akslen LA +16 more
core +2 more sources
Medicines, 2021 In spite of possessing desirable anticancer properties, currently, limited clinical success has been achieved with 20(S)-protopanaxadiol (aPPD) and 1,25-dihydroxyvitamin D3 (calcitriol).
Mohamed Ben-Eltriki +8 more
doaj +1 more source