Results 41 to 50 of about 49,400 (296)

Improved regeneration and de novo bone formation in a diabetic zebrafish model treated with paricalcitol and cinacalcet [PDF]

, 2017
Bone changes related to diabetes have been well stablished, but few strategies have been developed to prevent this growing health problem. In our work, we propose to investigate the effects of calcitriol as well as of a vitamin D analog (paricalcitol ...
Alvarez, Andress, Bergua, Bucking, Chan, Chen, Coyne, Coyne, Coyne, Craig, Cunha, Del Pino-Montes, Devaskar, Elder, Fishbane, Flanagan, Gagnon, Gavaia, Gehling, Goodman, Hamann, Hills, Illien-Junger, Irwin, Jayanarayanan, Jones, Katsumata, Keller, King, Kojima, Kojima, Kojima, Krul-Poel, Lee, Lehner, Lieschke, Lin, Maehata, Moss, Olsen, Pham-Short, Pipino, Pisharath, Pugliese, Rodriguez, Sanguineti, Schutter, Shoben, Sprague, Tsuruta, Tung, Westerfield, Wong, Zhao   +53 more
core   +1 more source

Budesonide and Calcitriol Synergistically Inhibit Airway Remodeling in Asthmatic Mice

Canadian Respiratory Journal, 2018
Background and Objective. While calcitriol can inhibit airway remodeling in asthmatic mice, the mechanism remains unclear. The purpose of this study was to explore the mechanism of action of calcitriol on airway remodeling in asthma and its interaction ...
Jun Qian, Yaqin Xu, Zhiwei Yu
doaj   +1 more source

Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent [PDF]

, 2016
BACKGROUND: Sarcoidosis is a multi-system disease characterized by the presence of non-caseating epithelioid granulomas in affected tissues, including skeletal muscle.
Eutsler, Eric Eutsler, Ferguson, Cole, Kitcharoensakkul, Maleewan, Orandi, Amir B, White, Andrew J   +4 more
core   +2 more sources

Therapeutic effects of vitamin D on acetic acid-induced colitis in rats [PDF]

Acta Cirúrgica Brasileira, 2020
Purpose To analyze the effect of calcitriol treatment on acute colitis in an experimental rat model. Methods A total of 24 adult Sprague Dawley albino rats were randomly separated into 3 equal groups: control group (n:8), colitis group (n:8 ...
Refik Bademci, Mümin Alper Erdoğan, Ali Yücel Kara, Gürkan Yiğittürk, Oytun Erbaş   +4 more
doaj   +1 more source

PD-L1 and calcitriol dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease.

JCI Insight, 2019
Autoimmune diseases resulting from MHC class II-restricted autoantigen-specific T cell immunity include the systemic inflammatory autoimmune conditions, rheumatoid arthritis and vasculitis.
Ryan C. Galea, H. Nel, Meghna Talekar, Xiao Liu, J. Ooi, M. Huynh, S. Hadjigol, K. Robson, Y. Ting, S. Cole, Karyn Cochlin, Shannon Hitchcock, Bijun Zeng, S. Yekollu, M. Boks, Natalie Goh, Helen Roberts, J. Rossjohn, J. Rossjohn, J. Rossjohn, H. Reid, B. Boyd, R. Malaviya, D. Shealy, D. Baker, L. Madakamutil, A. Kitching, B. O’Sullivan, Ranjeny Thomas   +28 more
semanticscholar   +1 more source

Effect of vitamin D supplementation on blood pressure:a systematic review and meta-analysis incorporating individual patient data [PDF]

, 2015
D-PRESSURE Collaboration: et al.[Importance]: Low levels of vitamin D are associated with elevated blood pressure (BP) and future cardiovascular events.
Alvarez, Jessica, Beveridge, Louise A., Boxer, Rebecca, Dalbeni, Andrea, Gepner, Adam D., Isbel, Nicole M., Jorde, Rolf, Khan, Faisel, Larsen, Thomas, Macdonald, Helen M., Nagpal, Jitender, Petchey, William G., Scragg, Robert, Stricker, Hans, Stroebel, Franziska, Struthers, Allan D., Tangpricha, Vin, Toxqui, Laura, Vaquero, M. Pilar, Wamberg, Louise, Witham, Miles D., Zittermann, Armin   +21 more
core   +3 more sources

Hypercalcemia in Lung Cancer due to Simultaneously Elevated PTHrP and Ectopic Calcitriol Production: First Case Report

Case Reports in Oncological Medicine, 2017
Calcitriol-mediated hypercalcemia has been reported in malignant lymphomas and granulomatous diseases but not in lung carcinoma. We describe a patient with squamous cell lung carcinoma with hypercalcemia and elevated calcitriol levels.
Saed Nemr, Sunitha Alluri, Dhivya Sundaramurthy, Daniel Landry, Gregory Braden   +4 more
doaj   +1 more source

Synergistic Antitumorigenic Activity of Calcitriol with Curcumin or Resveratrol is Mediated by Angiogenesis Inhibition in Triple Negative Breast Cancer Xenografts

Cancers, 2019
Calcitriol is a multitarget anticancer hormone; however, its effects on angiogenesis remain contradictory. Herein, we tested whether the antiangiogenic phytochemicals curcumin or resveratrol improved calcitriol antitumorigenic effects in vivo.
Janice García-Quiroz, R. García-Becerra, C. Santos-Cuevas, Gerardo J. Ramírez-Nava, Gabriela Morales-Guadarrama, Nohemí Cárdenas-Ochoa, Mariana Segovia-Mendoza, H. Prado-García, D. Ordaz-Rosado, E. Avila, A. Olmos-Ortíz, Sofía López-Cisneros, F. Larrea, L. Díaz   +13 more
semanticscholar   +1 more source

Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia [PDF]

, 2013
BACKGROUND: Chemotherapy-induced hair loss (alopecia) (CIA) is one of the most feared side effects of chemotherapy among cancer patients. There is currently no pharmacological approach to minimize CIA, although one strategy that has been proposed ...
Chu, Jennifer, Deslongchamps, Pierre, Dow, Lukas E., Lowe, Scott W., Nasr, Zeina, Paquet, Marilene, Pelletier, Jerry, Porco, John A., Ravindar, Kontham, Somaiah, Ragam   +9 more
core   +2 more sources

TGF-β1 stimulation and VDR-dependent activation modulate calcitriol action on skeletal muscle fibroblasts and Smad signalling-associated fibrogenesis

Scientific Reports, 2023
Fibroblasts play a pivotal role in fibrogenesis after skeletal muscle injury. Excess fibrous formation can disrupt contractile functions and delay functional recovery.
Ratchakrit Srikuea, Muthita Hirunsai
doaj   +1 more source