Results 61 to 70 of about 42,581 (243)

Parathyroid Hormone Sampling From the Anterior Jugular Vein Versus Peripheral Vein After Total Thyroidectomy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background To determine if anterior jugular vein sampling (AJVS) is non‐inferior to peripheral venous sampling (PVS) for measuring intraoperative parathyroid hormone (PTH) levels following total thyroidectomy. Methods This was a prospective non‐inferiority trial conducted at a tertiary academic medical center.
Noel M. Phan, Keva Li, Eleni A. Varelas, Caleb J. Fan, Raymond L. Chai   +4 more
wiley   +1 more source

Total Parathyroidectomy with Subcutaneous Parathyroid Forearm Autotransplantation in the Treatment of Secondary Hyperparathyroidism: A Single-Center Experience. [PDF]

, 2018
Introduction Secondary hyperparathyroidism is common in chronic kidney disease. Parathyroidectomy is indicated in refractory hyperparathyroidism when medical treatments and so the parathyroid hormone levels cannot be lowered to acceptable values without
Casella, Claudio, Dimko, Mira, Galani, Alessandro, Lai, Silvia, Ministrini, Silvia, Nazario Portolani, And, Totaro, Luigi   +6 more
core   +1 more source

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng, Alafate Abudouwanli, Quan Sun, Yi Tan, Wanchen Zhao, Mengyao Yang, Shan Wang, Hideoki Ogawa, Ko Okumura, François Niyonsaba   +9 more
wiley   +1 more source

The Investigation of the Effects of Calcitriol on Human Ovarian Carcinoma Cells

Ahi Evran Medical Journal
Purpose: Ovarian cancer is the fifth leading cause of cancer death in women, leading cause of death from gynecologic malignancies, and the second most commonly diagnosed gynecologic malignancy, however the underlying pathophysiology is not clearly ...
10.46332/aemj.1228216, Ebru Alimoğulları   +1 more
doaj   +1 more source

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, EarlyView.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

SAT-512 Severe Hypocalcemia Presenting as Status Epilepticus after Denosumab Use in Metastatic Prostate Cancer [PDF]

, 2019
Introduction: Denosumab decreases the incidence of skeletal-related events in patients with metastatic bone disease and is used routinely as part of the therapeutic strategy for various cancers.
Aziz, Ammara, Saeed, Zeb
core   +1 more source

Dual effect of vitamin D3 on breast cancer-associated fibroblasts

BMC Cancer
Background Cancer-associated fibroblasts (CAFs) play an important role in the tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 (VD3), its impact on breast CAFs is almost unknown.
Natalia Łabędź, Artur Anisiewicz, Martyna Stachowicz-Suhs, Joanna Banach, Dagmara Kłopotowska, Adam Maciejczyk, Patrycja Gazińska, Aleksandra Piotrowska, Piotr Dzięgiel, Rafał Matkowski, Joanna Wietrzyk   +10 more
doaj   +1 more source

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

Beilstein Journal of Nanotechnology, 2015
Poly(lactic-co-glycolic acid) (PLGA) nanoparticles were studied as drug delivery vehicles for calcitriol, the active form of vitamin D3. In vitro effects of calcitriol encapsulated in PLGA nanoparticles were evaluated with respect to free calcitriol on ...
Maria J. Ramalho, Joana A. Loureiro, Bárbara Gomes, Manuela F. Frasco, Manuel A. N. Coelho, M. Carmo Pereira   +5 more
doaj   +1 more source

Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism

Cells, 2020
Hypoxia-inducible transcription factors 1 and 2 (HIFs) are major mediators of cancer development and progression and validated targets for cancer therapy.
Ioanna-Maria Gkotinakou, Eleni Kechagia, Kalliopi Pazaitou-Panayiotou, Ilias Mylonis, Panagiotis Liakos, Andreas Tsakalof   +5 more
doaj   +1 more source

The Oldest Traces of Alcoholic Beverages in the Border Zone of the North and East European Plains

Archaeometry, EarlyView.
ABSTRACT Analysis of organic compounds preserved on pottery from the Bell Beaker community and the initial phase of the Trzciniec Cultural Sphere in the border zone of the Eastern and North European Plains was prompted by traces of alcoholic beverages found in contextually and formally analogous discoveries of more westerly provenance.
Dariusz Manasterski, Katarzyna Januszek, Angelina Rosiak, Aleksandra Cetwińska, Joanna Kałużna‐Czaplińska   +4 more
wiley   +1 more source