Results 61 to 70 of about 21,185 (156)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

PTH suppression by calcitriol does not predict off‐target actions in experimental CKD

open access: yesPharmacology Research & Perspectives, 2020
Vitamin D receptor agonist (VDRA) therapy for PTH suppression is a mainstay for patients with severe CKD. Calcitriol (1,25‐(OH)2D3) is a former first‐line VDRA in CKD treatment.
Bruno A. Svajger   +8 more
doaj   +1 more source

Vitamin D and Bladder Cancer Risk: An Umbrella Review and Second Order Meta‐Analysis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction Bladder cancer is a common malignancy with a high recurrence rate, posing a significant public health burden. Beyond its role in bone health, vitamin D has been suggested to influence cancer risk, including bladder cancer. Aim To evaluate the association between serum vitamin D levels, dietary intake, and supplementation with ...
Stefano Mancin   +10 more
wiley   +1 more source

Protective effects of ascorbic acid and calcitriol combination on airway remodelling in ovalbumin-induced chronic asthma

open access: yesPharmaceutical Biology, 2020
Context Airway remodelling is one of the most refractory problems in asthma. According to the critical roles of oxidative stress and inflammation in airway remodelling, it is supposed that ascorbic acid and calcitriol have beneficial effects.
Farzaneh Kianian   +5 more
doaj   +1 more source

Fahr's Syndrome in a Young Adult Male: A Case of Seizure and Cognitive Decline Secondary to Hypoparathyroidism

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Fahr's syndrome is a rare neurological condition characterized by bilateral intracranial calcifications secondary to metabolic or endocrine abnormalities, most commonly hypoparathyroidism. This condition is distinct from Fahr's disease (primary familial brain calcification), which is genetically inherited.
Sarah Nisar   +7 more
wiley   +1 more source

Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia

open access: yesScientific Reports
The annual increase in myopia prevalence poses a significant economic and health challenge. Our study investigated the effect of calcitriol role in myopia by inducing the condition in guinea pigs through form deprivation for four weeks.
Rongbin Liang   +6 more
doaj   +1 more source

The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
The vitamin D receptor (VDR) regulates hair follicle biology through ligand‐dependent and ligand‐independent mechanisms by heterodimerizing with retinoid X receptor, recruiting coactivator complexes, and activating target genes including Wnt inhibitors, hair keratins, and cell cycle regulators.
Liancheng Guan   +8 more
wiley   +1 more source

Vitamin D Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Models Relevant to Connective Tissue Disease–Associated Pulmonary Arterial Hypertension

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Mechanism study of VD mediated inflammatory and mitochondrial homeostasis in early PAH progression. ABSTRACT Vitamin D (VD) deficiency is prevalent in chronic inflammatory disorders and has been implicated in cardiopulmonary diseases. This study investigated whether VD, as a nutritional factor, modulates inflammatory and mitochondrial homeostasis in ...
Yansheng Jin   +4 more
wiley   +1 more source

Segmental Tracheal Resection for Thyroid Cancer: Perioperative Morbidity, Locoregional Control, and Survival

open access: yesHead &Neck, Volume 48, Issue 3, Page 644-649, March 2026.
ABSTRACT Background Segmental tracheal resection is rarely needed for advanced thyroid cancer but is among the most complex, high‐risk thyroid surgeries. Methods Retrospective study of patients undergoing segmental tracheal resection for thyroid cancer at MD Anderson Cancer Center (2005–2024).
Anastasios Maniakas   +19 more
wiley   +1 more source

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

open access: yesThe Journal of Dermatology, Volume 53, Issue 3, Page 372-379, March 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng   +9 more
wiley   +1 more source

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