Results 61 to 70 of about 49,400 (296)

Calcitriol Elevation is Associated with a Higher Risk of Refractory Hypercalcemia of Malignancy in Solid Tumors.

Journal of Clinical Endocrinology and Metabolism, 2019
BACKGROUND Hypercalcemia of malignancy (HCM) is a common complication of advanced cancer. Parathyroid hormone (PTH)-independent HCM may be mediated through different mechanisms: 1) humoral HCM, caused by the secretion of parathyroid hormone-related ...
Tariq Chukir, Yi Liu, K. Hoffman, J. Bilezikian, A. Farooki   +4 more
semanticscholar   +1 more source

Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice [PDF]

, 2015
ADO2 is a heritable osteosclerotic disorder that usually results from heterozygous missense dominant negative mutations in the chloride channel 7 gene (CLCN7).
Acton, Dena, Alam, Imranul, Econs, Michael J., Gerard-O'Riley, Rita L., Gray, Amie K., Reilly, Austin M.   +5 more
core   +1 more source

Vitamin D deficiency in a subfertility population and the impact of COVID‐19 lockdowns

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the burden of vitamin D deficiency in female patients attending a fertility clinic in a tertiary referral center, assess temporal trends—including the potential impact of COVID‐19 lockdowns—and explore socioeconomic disparities in vitamin D levels.
Catherine M. Windrim, Daniel Kane, Grainne Kelleher, Edgar Mocanu   +3 more
wiley   +1 more source

Association of Short‐Term Wildfire Air Pollution Exposure and Health Care Usage: A Cross‐Sectional Study Among Patients With Psoriasis From the Bay Area, United States

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Wildfire air pollution causes many adverse environmental and health effects, including adverse skin reactions. However, whether wildfire‐associated air pollution and psoriasis disease activity are associated remains unknown. Objectives To examine the association between short‐term exposure to air pollution from wildfires and rates ...
Johan Anker Chrom Allerup, Somaia Naassan, Zarqa Ali, Justin M. Ko, Kenneth Thomsen, Simon Francis Thomsen   +5 more
wiley   +1 more source

Calcitriol and energy metabolism [PDF]

Nutrition Reviews, 2008
Calcitriol, a calcitrophic hormone that can be suppressed by high dietary calcium, favors fatty acid synthesis and inhibits lipolysis via non-genomic modulation of Ca(2+) influx. Calcitriol also suppresses UCP2 expression via the nVDR and thereby increases energy efficiency. Calcitriol exerts a dose-dependent impact on adipocyte apoptosis and regulates
Xiaocun Sun, Michael B. Zemel
openaire   +2 more sources

Multi‐Omics Analysis of Ileal Mucosa and Mesentery Before and After Ileocecal Resection in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic disorder involving any part of the gastrointestinal tract. Ileocecal resection may serve as a more effective treatment option for early CD. However, the potential relationship and mechanisms between the ileocecum and remission induction of CD are still elusive.
Kai Xia, Yiran Jiao, Luoqiu Zhang, Renyuan Gao, Fangtao Wang, Yun Pan, Shuang Cui, Yin Lin, Tianqi Wu, Lin Li, Xiaocai Wu, Yu Ruan, Jing Sun, Lu Yin, Chunqiu Chen, Moubin Lin   +15 more
wiley   +1 more source

Calcitriol enhances pyrazinamide treatment of murine tuberculosis

Chinese Medical Journal, 2019
. Background:. Tuberculosis is a leading cause of morbidity and mortality in humans worldwide. There is an urgent need for new and effective drugs to treat tuberculosis and shorten the duration of tuberculosis therapy.
Jing Zhang, Ming Guo, Zhi-Xiang Huang, Rong Bao, Qian Yu, Ming Dai, Xin Wang, Yan Rao, Peng Lyu   +8 more
doaj   +1 more source

Calcitriol Prevents RAD51 Loss and cGAS‐STING‐IFN Response Triggered by Progerin

Proteomics, 2019
Hutchinson Gilford progeria syndrome (HGPS) is a devastating accelerated aging disease caused by LMNA gene mutation. The truncated lamin A protein produced “progerin” has a dominant toxic effect in cells, causing disruption of nuclear architecture and ...
Nuria Coll-Bonfill, Rafael Cançado de Faria, Sweta Bhoopatiraju, S. Gonzalo   +3 more
semanticscholar   +1 more source

Mineral Homeostasis in Murine Fetuses Is Sensitive to Maternal Calcitriol but Not to Absence of Fetal Calcitriol [PDF]

Journal of Bone and Mineral Research, 2018
ABSTRACT   Vitamin D receptor (VDR) null fetuses have normal serum minerals, parathyroid hormone (PTH), skeletal morphology, and mineralization but increased serum calcitriol, placental calcium transport, and placental expression of Pthrp, Trpv6, and (as reported in this study) Pdia3.
René St-Arnaud, Martin Kaufmann, Kamal Alhani, Glenville Jones, Beth J. Kirby, Brittany A. Ryan, Christopher S. Kovacs, K. Berit Sellars   +7 more
openaire   +3 more sources

Suspected calcitriol‐mediated hypercalcaemia and postmortem diagnosis of histiocytic sarcoma in a dog

Veterinary Record Case Reports, EarlyView.
Abstract This report describes a case of refractory ionised hypercalcaemia, of 12 months duration, in an 11‐year‐old, male, neutered beagle diagnosed with metastatic histiocytic sarcoma at postmortem examination. In this case, the parathyroid hormone levels were at the lower end of the reference interval, the parathyroid hormone‐related peptide was ...
Kerry E. Rolph, Mollie McBride, Gilda Rawlins‐Vaughan, Sarah Cavanaugh, Regina Tose Kemper, Pompei Bolfa   +5 more
wiley   +1 more source