Results 161 to 170 of about 3,615,813 (279)

An updated investigation on the dromedary camel cerebellum (Camelus dromedarius) with special insight into the distribution of calcium-binding proteins. [PDF]

Sci Rep, 2020
Attaai AH, Noreldin AE, Abdel-Maksoud FM, Hussein MT.   +3 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

NECAB family of neuronal calcium-binding proteins in health and disease. [PDF]

Neural Regen Res
Bueno D, Schäfer MKE, Wang S, Schmeisser MJ, Methner A.   +4 more
europepmc   +1 more source

Studies on calcium-binding proteins

, 1984
A method was improved to detect ('45)Ca('2+)-binding proteins in polyacrylamide gels. It was shorter, quantitative, highly reproducible, and resulted in a 40-fold enhanced sensitivity over the previous method.
Anthony, Francis Andrew
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Stress enhances expression of calcium-binding proteins and NMDAR subunit genes in the rat hippocampus. [PDF]

Neuroprotection
Parthasarathy A, Hanumanthappa R, Bulbule SR, P C K, Nanjaiah H, G G, B M S, Muniswamy D, Kuramkote Shivanna D.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Distribution of calcium-binding proteins immunoreactivity in the bottlenose dolphin entorhinal cortex. [PDF]

Front Neuroanat
Graïc JM, Grandis A, Sacchini S, Tagliavia C, Salamanca G, Cozzi B, Bombardi C.   +6 more
europepmc   +1 more source

Structural properties of target binding by profilaggrin A and B domains and other S100 fused-type calcium-binding proteins. [PDF]

J Dermatol Sci, 2020
Hinbest AJ, Kim SR, Eldirany SA, Lomakin IB, Watson J, Ho M, Bunick CG.   +6 more
europepmc   +1 more source