Results 41 to 50 of about 3,593,980 (394)
Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons [PDF]
, 2002 Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and ...
Boccaccio, A +4 more
core +1 more source
Medicine, 2003 Overdose of calcium channel blockers is potentially lethal. Verapamil and diltiazem are much more dangerous than dihydropyridines. Hypotension with (verapamil and diltiazem) or without (dihydropyridines) heart block and bradycardia are the most important features.
Buckley, Nicholas +2 more
openaire +2 more sources
Frontiers in Cellular Neuroscience, 2019 Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann +2 more
doaj +1 more source
SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification. [PDF]
PLoS Genetics, 2016 The C. elegans AWC olfactory neuron pair communicates to specify asymmetric subtypes AWCOFF and AWCON in a stochastic manner. Intercellular communication between AWC and other neurons in a transient NSY-5 gap junction network antagonizes voltage ...
Amel Alqadah +8 more
doaj +1 more source
A chloride channel in rat and human axons [PDF]
, 1991 Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker +19 more
core +1 more source
Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
, 2018 Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan +10 more
core +1 more source
Nature Communications, 2016 Mounting in vitro, in vivo and clinical evidence suggest an important role for filopodia in driving cancer cell invasion. Using a high-throughput microscopic-based drug screen, we identify FDA-approved calcium channel blockers (CCBs) as potent inhibitors
Guillaume Jacquemet +10 more
semanticscholar +1 more source
Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications
Canadian Respiratory Journal, 1997 Electrophysiological and pharmacological techniques were used to characterize the membrane conductance changes underlying spasmogen-evoked depolarization in airway smooth muscle (ASM).
Luke J Janssen
doaj +1 more source
T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis
Frontiers in Endocrinology, 2016 Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier +1 more
doaj +1 more source
Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. [PDF]
PLoS ONE, 2013 Calcium-activated potassium channels of the KCa1.1 class are known to regulate repolarization of action potential discharge through a molecular association with high voltage-activated calcium channels.
Renata Rehak +5 more
doaj +1 more source