Results 41 to 50 of about 503,305 (349)
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family [PDF]
, 2013 We use Brownian dynamics (BD) simulations to study the ionic conduction and valence selectivity of a generic electrostatic model of a biological ion channel as functions of the fixed charge Qf at its selectivity filter.
Eisenberg, Robert S. +4 more
core +2 more sources
Suramin-Induced Neurotoxicity: Preclinical Models and Neuroprotective Strategies
Molecules, 2018 Suramin is a trypan blue analogon originally developed to treat protozoan infections, which was found to have diverse antitumor effects. One of the most severe side effects in clinical trials was the development of a peripheral sensory-motor ...
David von der Ahe +5 more
doaj +1 more source
CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
eLife, 2023 Activation of voltage-gated calcium channels at presynaptic terminals leads to local increases in calcium and the fusion of synaptic vesicles containing neurotransmitter.
Brian D Mueller +12 more
doaj +1 more source
TRP channels in microglia: role in physiology and disease
Frontiers in Cellular Neuroscience, 2015 Microglia are responsible for modulating the cellular environment in the nervous system, where they have neuroprotective effects. In these cells has been reported the expression of different ion channels, including those belonging to the transient ...
Yolima P Torres
doaj +1 more source
Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]
, 2016 © 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L. +3 more
core +2 more sources
The roles of the subunits in the function of the calcium channel [PDF]
, 1991 Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin +5 more
core +1 more source
Frontiers in Cellular Neuroscience, 2015 Photoreceptors rely upon highly specialized synapses to efficiently transmit signals to multiple postsynaptic targets. Calcium influx in the presynaptic terminal is mediated by voltage-gated calcium channels (VGCC).
Antonella eCaputo +6 more
doaj +1 more source
Root growth and signalling: the role of calcium channels [PDF]
, 2017 Roots acquire calcium not only as a macronutrient but also to serve as a second messenger in signalling and a component of exocytosis for growth. Plasma membrane channels are sufficient to deliver calcium from the apoplast to the cytosol to enable its ...
Davies, Julia M.
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2. [PDF]
, 2004 Mammalian voltage-gated K+ channels are assemblies of pore-forming alpha-subunits and modulating beta-subunits. To operate correctly, Kv4 alpha-subunits in the heart and central nervous system require recently identified beta-subunits of the neuronal ...
Butler, Margaret H +5 more
core