Results 71 to 80 of about 315,890 (238)
SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells
Biological Research, 2000 The effects of redox reagents on the activity of the intracellular calcium release channels (ryanodine receptors) of skeletal and cardiac muscle, or brain cortex neurons, was examined. In lipid bilayer experiments, oxidizing agents (2,2'-dithiodipyridine
CECILIA HIDALGO +4 more
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Role of calcium-activated potassium channels in the heart
Cardiology Plus, 2017 Ability of intracellular calcium to open K+-selective channels in an excitable membrane and to hasten repolarization of an action potential or inhibit firing is a fundamental principle of biology first recognized in the mid-1970s. There are several types
William T Clusin
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T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B
Molecular Brain, 2018 This study describes the functional interaction between the Cav3.1 and Cav3.2 T-type calcium channels and cytoskeletal spectrin (α/β) and ankyrin B proteins.
Agustin Garcia-Caballero +10 more
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Quantitative aspects of L-type calcium currents [PDF]
arXiv, 2011 Calcium currents in neurons and muscle cells have been classified as being one of 5 types of which four, L, N, P/Q and R were said to be high threshold and one, T, was designated low threshold. This review focuses on quantitative aspects of L-type currents.
arxiv
Calcium Channel Blockers and Hypertension
Journal of Cardiovascular Pharmacology and Therapeutics, 2014 Effective treatment of high blood pressure (BP) represents a key strategy for reducing the burden of hypertension-related cardiovascular and renal diseases. In spite of these well-established concepts, hypertension remains poorly controlled worldwide.
TOCCI, GIULIANO +6 more
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Calcium-permeable ion channels in control of autophagy and cancer
Frontiers in Physiology, 2013 Autophagy, or cellular self-eating, is a tightly regulated cellular pathway the main purpose of which is lysosomal degradation and subsequent recycling of cytoplasmic material to maintain normal cellular homeostasis.
Artem eKondratskyi +5 more
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Journal of Cell Biology, 2009 Thanks to a protein that helps fruit flies remain airborne, researchers have deciphered a key step in synapse maturation. [Fouquet et al.][1] show that the protein forms part of a synaptic structure that clusters the calcium channels necessary for neurotransmitter release.
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Molecular Neurodegeneration, 2011 Background Familial amyloidotic polyneuropathy (FAP) is a peripheral neuropathy caused by the extracellular accumulation and deposition of insoluble transthyretin (TTR) aggregates. However the molecular mechanism that underlies TTR toxicity in peripheral
Vincent Adele J +7 more
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The Journal of Cell Biology, 2007 ![][1] Calcium channels (red) cluster at presynaptic termini, but not without SMN (right). A paralyzing disease might best be treated by exciting motoneurons rather than saving them, report [Jablonka et al.][2] The paralysis that occurs in patients with spinal muscular atrophy ...
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