Results 11 to 20 of about 7,712,280 (384)
Calcium imaging for analgesic drug discovery
Neurobiology of Pain, 2022 Somatosensation and pain are complex phenomena involving a rangeofspecialised cell types forming different circuits within the peripheral and central nervous systems.
Federico Iseppon +2 more
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Genetically engineered mice for combinatorial cardiovascular optobiology
eLife, 2021 Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. However, the combination of these optical tools in mice
Frank K Lee +14 more
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Nature Communications, 2022 In vivo two-photon calcium imaging is a powerful approach in neuroscience. However, processing two-photon calcium imaging data is computationally intensive and time-consuming, making online frame-by-frame analysis challenging. This is especially true for
Luca Sità +6 more
semanticscholar +1 more source
Growth hormone treatment improves final height in children with X-linked hypophosphatemia
Orphanet Journal of Rare Diseases, 2022 Background/aim Despite optimal conventional treatment (oral phosphate supplements and active vitamin D analogs), about 40–50% of children with well-controlled X-linked hypophosphatemia (XLH) show linear growth failure, making them less likely to achieve ...
Julia André +8 more
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Characterizing Cortex-Wide Dynamics with Wide-Field Calcium Imaging
Journal of Neuroscience, 2021 The brain functions through coordinated activity among distributed regions. Wide-field calcium imaging, combined with improved genetically encoded calcium indicators, allows sufficient signal-to-noise ratio and spatiotemporal resolution to afford a ...
Chi Ren, T. Komiyama
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Cell type-specific calcium imaging of central sensitization in mouse dorsal horn
Nature Communications, 2022 Allodynia is a state in which pain is elicited by innocuous stimuli. Capsaicin applied to the skin results in an allodynia that extends to a broad region beyond the application site.
Charles A. Warwick +8 more
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Frontiers in Cell and Developmental Biology, 2020 X-linked hypophosphatemia (XLH) is characterized by rickets and osteomalacia, caused by inactivating mutations in the Phosphate-regulating endopeptidase homolog X-linked (PHEX) gene.
Carole-Anne Faraji-Bellée +19 more
doaj +1 more source
Nature Communications, 2021 Calcium imaging is an increasingly valuable technique for understanding neural circuits, neuroethology, and cellular mechanisms. The analysis of calcium imaging data presents challenges in image processing, data organization, analysis, and accessibility.
Kushal Kolar +4 more
semanticscholar +1 more source
Recent Advances of Calcium Carbonate Nanoparticles for Biomedical Applications
Bioengineering, 2022 Calcium carbonate nanoparticles have been widely used in biomedicine due to their biocompatibility and biodegradability. Recently, calcium carbonate nanoparticles are largely integrated with imaging contrast and therapeutic agents for various imaging and
Pengxuan Zhao +4 more
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A hardware system for real-time decoding of in vivo calcium imaging data
eLife, 2023 Epifluorescence miniature microscopes (‘miniscopes’) are widely used for in vivo calcium imaging of neural population activity. Imaging data are typically collected during a behavioral task and stored for later offline analysis, but emerging techniques ...
Zhe Chen +9 more
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