Go with the FLOW: visualizing spatiotemporal dynamics in optical widefield calcium imaging [PDF]
Journal of the Royal Society Interface, 2020 Widefield calcium imaging has recently emerged as a powerful experimental technique to record coordinated large-scale brain activity. These measurements present a unique opportunity to characterize spatiotemporally coherent structures that underlie ...
Nathaniel J. Linden +5 more
semanticscholar +1 more source
Bio-Protocol, 2017 Fertilization calcium waves are a conserved trigger for animal development; however, genetic analysis of these waves has been limited due to the difficulty of imaging in vivo fertilization.
Jun Takayama +2 more
doaj +1 more source
Long-term prognosis for individuals with hypertension undergoing coronary artery calcium scoring [PDF]
, 2015 To examine the performance of coronary artery calcification (CAC) for stratifying long-term risk of death in asymptomatic hypertensive ...
Callister, Tracy Q +14 more
core +1 more source
Calcium Sensor for Photoacoustic Imaging
Journal of the American Chemical Society, 2017 We introduce a selective and cell-permeable calcium sensor for photoacoustics (CaSPA), a versatile imaging technique that allows for fast volumetric mapping of photoabsorbing molecules with deep tissue penetration. To optimize for Ca2+-dependent photoacoustic signal changes, we synthesized a selective metallochromic sensor with high extinction ...
Sheryl Roberts +17 more
openaire +5 more sources
High-Throughput Platform for Optoacoustic Probing of Genetically Encoded Calcium Ion Indicators
iScience, 2019 Summary: Functional optoacoustic (OA) imaging assisted with genetically encoded calcium ion indicators (GECIs) holds promise for imaging large-scale neuronal activity at depths and spatiotemporal resolutions not attainable with existing optical ...
Urs A.T. Hofmann +6 more
doaj +1 more source
Dendritic spike saturation of endogenous calcium buffer and induction of postsynaptic cerebellar LTP. [PDF]
PLoS ONE, 2008 The architecture of parallel fiber axons contacting cerebellar Purkinje neurons retains spatial information over long distances. Parallel fiber synapses can trigger local dendritic calcium spikes, but whether and how this calcium signal leads to plastic ...
Marco Canepari, Kaspar E Vogt
doaj +1 more source
Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation [PDF]
, 2013 Kassing V, Engelmann J, Kurtz R. Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation. PLoS ONE.
Engelmann, Jacob +2 more
core +4 more sources
Cell Calcium Imaging as a Reliable Method to Study Neuron–Glial Circuits
Frontiers in Neuroscience, 2020 Complex dynamic cellular networks have been studied in physiological and pathological processes under the light of single-cell calcium imaging (SCCI), a method that correlates functional data based on calcium shifts operated by different intracellular ...
R. A. de Melo Reis +2 more
semanticscholar +1 more source
Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. [PDF]
, 2018 To uncover the circuit-level alterations that underlie atypical sensory processing associated with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1-/-) mouse model of Fragile X syndrome.
A Contractor +53 more
core +2 more sources
Calcium Imaging and the Curse of Negativity
bioRxiv, 2020 The imaging of neuronal activity using calcium indicators has become a staple of modern neuroscience. However, without ground truths, there is a real risk of missing a significant portion of the real responses. Here, we show that a common assumption, the
Gilles C. Vanwalleghem +2 more
semanticscholar +1 more source