Results 71 to 80 of about 2,340,161 (352)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Correlation between Serum Calcium and Phosphate with Coronary Artery Calcium Scores on Cardiac MSCT Examination

open access: yesSaintika Medika, 2019
Increased serum calcium and phosphate associated with cardiovascular disease in patients with chronic kidney disease, but research on the relationship between coronary artery calcium scores with serum calcium and phosphate in individuals with normal ...
Rosita Kai   +4 more
doaj   +1 more source

Response of Npt2a knockout mice to dietary calcium and phosphorus. [PDF]

open access: yesPLoS ONE, 2017
Mutations in the renal sodium-dependent phosphate co-transporters NPT2a and NPT2c have been reported in patients with renal stone disease and nephrocalcinosis, but the relative contribution of genotype, dietary calcium and phosphate to the formation of ...
Yuwen Li   +8 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Obtaining octacalium phosphate in aqueous medium during the interaction of calcite with monocalcium phosphate monohydrate

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
Calcium phosphate composite powders consisting of brushite and calcite were obtained in an aqueous medium from a CaCO3/Ca(H2PO4)2 suspension at Ca/P ratios of 1,33, 1,50, 1,67, pH 5–7, and maturation time of 21-50 days.
V.K. Krut’ko   +3 more
doaj   +1 more source

Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic [PDF]

open access: yes, 2008
Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1.
Blitterswijk, Clemens A. van   +3 more
core   +2 more sources

Precise synthesis of unique polydopamine/mesoporous calcium phosphate hollow Janus nanoparticles for imaging-guided chemo-photothermal synergistic therapy† †Electronic supplementary information (ESI) available: FTIR spectroscopy, UV-vis absorption spectra, XRD, etc. See DOI: 10.1039/c7sc03521g

open access: yesChemical Science, 2017
A novel synthetic strategy has been developed for fabricating spherical polydopamine/mesoporous calcium phosphate (PDA/mCaP) hollow Janus nanoparticles (H-JNPs).
Manjie Zhang   +5 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Calcium chloride in neonatal parenteral nutrition: compatibility studies using laser methodology. [PDF]

open access: yesPLoS ONE, 2014
We have previously reported results of precipitation studies for neonatal parenteral nutrition solutions containing calcium chloride and sodium phosphate using visual methods to determine compatibility. The purpose of this study was to do further testing
Robert K Huston   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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