Results 1 to 10 of about 2,982,557 (298)
Calcium signal compartmentalization
Biological Research, 2002 Cytosolic calcium signals are produced by suddenly increasing the concentration of free calcium ions (Ca2+). This can occur by opening channels permeable to Ca2+ either in the surface cell membrane or in the membranes of intracellular organelles ...
OLE H. PETERSEN
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An open source tool for automatic spatiotemporal assessment of calcium transients and local 'signal-close-to-noise' activity in calcium imaging data. [PDF]
PLoS Computational Biology, 2018 Local and spontaneous calcium signals play important roles in neurons and neuronal networks. Spontaneous or cell-autonomous calcium signals may be difficult to assess because they appear in an unpredictable spatiotemporal pattern and in very small ...
Juan Prada +5 more
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eLife, 2023 Thymus-originated tTregs and in vitro induced iTregs are subsets of regulatory T cells. While they share the capacity of immune suppression, their stabilities are different, with iTregs losing their phenotype upon stimulation or under inflammatory milieu.
Huiyun Lyu +9 more
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Calcium Signaling in Plant Programmed Cell Death
Cells, 2021 Programmed cell death (PCD) is a process intended for the maintenance of cellular homeostasis by eliminating old, damaged, or unwanted cells. In plants, PCD takes place during developmental processes and in response to biotic and abiotic stresses.
Huimin Ren +5 more
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ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain
eLife, 2021 Accumulating evidence has shown transcranial low-intensity ultrasound can be potentially a non-invasive neural modulation tool to treat brain diseases.
Jormay Lim +13 more
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Function of Protein Kinases in Leaf Senescence of Plants
Frontiers in Plant Science, 2022 Leaf senescence is an evolutionarily acquired process and it is critical for plant fitness. During senescence, macromolecules and nutrients are disassembled and relocated to actively growing organs.
Fengbo Yang +6 more
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H2O2 and Ca2+ Signaling Crosstalk Counteracts ABA to Induce Seed Germination
Antioxidants, 2022 Seed germination is a critical stage and the first step in the plant’s life cycle. H2O2 and Ca2+ act as important signal molecules in regulating plant growth and development and in providing defense against numerous stresses; however, their crosstalk in ...
Mengjie Cheng +9 more
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Role of Gamma-Aminobutyric Acid in Plant Defense Response
Metabolites, 2023 Gamma-aminobutyric acid (GABA) is a four-carbon non-protein amino acid that acts as a defense substance and a signaling molecule in various physiological processes, and which helps plants respond to biotic and abiotic stresses. This review focuses on the
Zhujuan Guo +4 more
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The transient receptor potential channels in rheumatoid arthritis: Need to pay more attention
Frontiers in Immunology, 2023 Rheumatoid arthritis (RA) is characterized by the augment of vascular permeability, increased inflammatory cells infiltration, dysregulated immune cells activation, pannus formation and unbearable pain hyperalgesia.
Mengwen Niu +4 more
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TRPM2: bridging calcium and ROS signaling pathways—implications for human diseases
Frontiers in Physiology, 2023 TRPM2 is a versatile and essential signaling molecule that plays diverse roles in Ca2+ homeostasis and oxidative stress signaling, with implications in various diseases. Research evidence has shown that TRPM2 is a promising therapeutic target.
Maria Maliougina, Yassine El Hiani
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