Results 31 to 40 of about 2,982,557 (298)

Target cell-specific plasticity rules of NMDA receptor-mediated synaptic transmission in the hippocampus

Frontiers in Cellular Neuroscience, 2023
Long-term potentiation and depression of NMDA receptor-mediated synaptic transmission (NMDAR LTP/LTD) can significantly impact synapse function and information transfer in several brain areas. However, the mechanisms that determine the direction of NMDAR
Stefano Lutzu, Karina Alviña, Nagore Puente, Nagore Puente, Pedro Grandes, Pedro Grandes, Pablo E. Castillo, Pablo E. Castillo   +7 more
doaj   +1 more source

Calcium Signaling in T Cells Is Induced by Binding to Nickel-Chelating Lipids in Supported Lipid Bilayers

Frontiers in Physiology, 2021
Supported lipid bilayers (SLBs) are one of the most common cell-membrane model systems to study cell-cell interactions. Nickel-chelating lipids are frequently used to functionalize the SLB with polyhistidine-tagged ligands. We show here that these lipids
Tommy Dam, Victoria Junghans, Jane Humphrey, Manto Chouliara, Peter Jönsson   +4 more
doaj   +1 more source

Analysis of EF-Hand Proteins in Soybean Genome Suggests Their Potential Roles in Environmental and Nutritional Stress Signaling

Frontiers in Plant Science, 2017
Calcium ion (Ca2+) is a universal second messenger that plays a critical role in plant responses to diverse physiological and environmental stimuli. The stimulus-specific signals are perceived and decoded by a series of Ca2+ binding proteins serving as ...
Houqing Zeng, Yaxian Zhang, Xiajun Zhang, Erxu Pi, Yiyong Zhu   +4 more
doaj   +1 more source

Gaining insight into the neural basis of resting-state fMRI signal

NeuroImage, 2022
The blood oxygenation level-dependent (BOLD)-based resting-state functional magnetic resonance imaging (rsfMRI) has been widely used as a non-invasive tool to map brain-wide connectivity architecture.
Zilu Ma, Qingqing Zhang, Wenyu Tu, Nanyin Zhang   +3 more
doaj   +1 more source

Calcium signaling in osteoclasts

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011
It has long been known that many bone diseases, including osteoporosis, involve abnormalities in osteoclastic bone resorption. As a result, there has been intense study of the mechanisms that regulate both the differentiation and bone resorbing function of osteoclast cells.
Hwang, Sung-Yong, Putney, James W.
openaire   +2 more sources

Intracellular calcium signaling [PDF]

Journal of Cell Science, 2002
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
openaire   +2 more sources

Calcium at the Crossroads of Signaling [PDF]

The Plant Cell, 2002
### Calcium Signals: A Central Paradigm in Stimulus–Response Coupling Cells must respond to an array of environmental and developmental cues. The signaling networks that have evolved to generate appropriate cellular responses are varied and are normally composed of elements that include ...
Dale, Sanders, Jérôme, Pelloux, Colin, Brownlee, Jeffrey F, Harper   +3 more
openaire   +2 more sources

Eudebeiolide B Inhibits Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Regulating RANKL-Induced NF-κB, c-Fos and Calcium Signaling

Pharmaceuticals, 2020
Eudebeiolide B is a eudesmane-type sesquiterpenoid compound isolated from Salvia plebeia R. Br., and little is known about its biological activity. In this study, we investigated the effects of eudebeiolide B on osteoblast differentiation, receptor ...
Mi-Hwa Kim, Hyung-Jin Lim, Seon Gyeong Bak, Eun-Jae Park, Hyun-Jae Jang, Seung Woong Lee, Soyoung Lee, Kang Min Lee, Sun Hee Cheong, Seung-Jae Lee, Mun-Chual Rho   +10 more
doaj   +1 more source

The vital role of TRPM2 in breast cancer cell proliferation and its difference in expression between non-Hispanic white and non-Hispanic black females [PDF]

World Cancer Research Journal
Objective: To study the racial disparity of transient receptor potential melastatin-related channel subtype 2 (TRPM2) expression in non-Hispanic black (NHB) women and non-Hispanic white women (NHW) breast cancer tissues.
L. Huang, Y. Lu, M. Li
doaj   +1 more source

Genetically Encoded Calcium Indicators Based on Troponin C and Fluorescent Proteins [PDF]

, 2005
Genetically encoded calcium probes allow the visualization and quantification of intracellular calcium dynamics with great specificity and sensitivity.
Heim, Nicola
core   +1 more source