Results 141 to 150 of about 2,982,557 (298)

SlHSP17.7 Ameliorates Chilling Stress-Induced Damage by Regulating Phosphatidylglycerol Metabolism and Calcium Signal in Tomato Plants. [PDF]

Plants (Basel), 2022
Wu Y, Lv S, Zhao Y, Chang C, Hong W, Jiang J.   +5 more
europepmc   +1 more source

Calcium signaling in crops

New Phytologist
Summary Calcium (Ca 2+ ) signaling is integral to nearly all aspects of plant biology, including development and responses to biotic and abiotic stresses. It operates through two main layers: the generation of Ca 2+ signals and their ...
Chunxia Zhang, Yang Song, Jörg Kudla
openaire   +3 more sources

The initiation of a calcium signal in Xenopus oocytes

, 1994
Application of acetylcholine to Xenopus oocytes evoked increases in the cytosolic free calcium ion concentration ([Ca2+]i) after latencies of up to several seconds depending on the agonist dose.
Petersen, C. C., Dupont, G., Dupont, Geneviève, Petersen, C H   +3 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids. [PDF]

SLAS Discov, 2022
Boutin ME, Strong CE, Van Hese B, Hu X, Itkin Z, Chen YC, LaCroix A, Gordon R, Guicherit O, Carromeu C, Kundu S, Lee E, Ferrer M.   +12 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

CDPKs: The critical decoders of calcium signal at various stages of malaria parasite development. [PDF]

Comput Struct Biotechnol J, 2021
Sharma M, Choudhury H, Roy R, Michaels SA, Ojo KK, Bansal A.   +5 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Calcium Signal Profiles in Vascular Endothelium from Cdh5-GCaMP8 and Cx40-GCaMP2 Mice. [PDF]

J Vasc Res, 2021
Chen YL, Baker TM, Lee F, Shui B, Lee JC, Tvrdik P, Kotlikoff MI, Sonkusare SK.   +7 more
europepmc   +1 more source

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels

, 2009
Human neutrophils express formyl peptide receptor 1 and 2 (FPR1 and FPR2), two highly homologous G-protein-coupled cell surface receptors important for the cellular recognition of chemotactic peptides.
Rabiet, Marie-Josèphe, Forsman, Huamei,, Karlsson, Jennie,, Bylund, Johan,, Dahlgren, Claes,, Stenfeldt, Anna-Lena,   +5 more
core   +1 more source