Results 271 to 280 of about 2,982,557 (298)
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Calcium signaling and apoptosis
Biochemical and Biophysical Research Communications, 2003Ca(2+) is one of the key regulators of cell survival, but Ca(2+) can also induce apoptosis in response to a variety of pathological conditions. The pro-apoptotic effects of Ca(2+) are mediated by a diverse range of Ca(2+)-sensitive factors that are compartmentalized in various intracellular organelles including the ER, cytoplasm, and mitochondria.
György, Hajnóczky +2 more
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Calcium Signaling in the Heart
2019The aim of this chapter is to discuss evidence concerning the many roles of calcium ions, Ca2+, in cell signaling pathways that control heart function. Before considering details of these signaling pathways, the control of contraction in ventricular muscle by Ca2+ transients accompanying cardiac action potentials is first summarized, together with a ...
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Calcium Signaling in the Islets
2010Easy access to rodent islets and insulinoma cells and the ease of measuring Ca(2+) by fluorescent indicators have resulted in an overflow of data that have clarified minute details of Ca(2+) signaling in the rodent islets. Our understanding of the mechanisms and the roles of Ca(2+) signaling in the human islets, under physiological conditions, has been
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Orchestration of Skin Stem Cell Layer by Calcium Signals
Nature Reviews Molecular Cell Biology, 2023Paulina Strzyz
exaly
2012
Ca2+ is an important signal transduction molecule that has been shown to regulate responses to a large number of environmental stimuli in plants and control many developmental processes. These stimuli induce the formation of Ca2+ signals within a cell, which are generated through the action of Ca2+ release and uptake from and into internal cellular ...
Bickerton, Peter D., Pittman, Jon K.
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Ca2+ is an important signal transduction molecule that has been shown to regulate responses to a large number of environmental stimuli in plants and control many developmental processes. These stimuli induce the formation of Ca2+ signals within a cell, which are generated through the action of Ca2+ release and uptake from and into internal cellular ...
Bickerton, Peter D., Pittman, Jon K.
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Calcium Signalling in Microglia
Intracellular Ca2+ signalling represents the substrate of microglial excitability. Spatially and temporally organised changes in the free cytoplasmic Ca2+ concentration ([Ca2+]i) are generated in response to physiological and pathological stimuli. Parameters of these intracellular Ca2+ signals are defined by Ca2+ signalling toolkits that may change ...Olga, Garaschuk, Alexei, Verkhratsky
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Critical reviews in oncogenesis, 1992
Calcium, the great signaler, is at the heart of proliferation, differentiation, and cancer. It figures prominently in the five signals that activate proliferatively quiescent normal cells and then trigger chromosome replication and mitosis. Calcium regulates intercellular communication through gap junctions and triggers the terminal differentiation ...
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Calcium, the great signaler, is at the heart of proliferation, differentiation, and cancer. It figures prominently in the five signals that activate proliferatively quiescent normal cells and then trigger chromosome replication and mitosis. Calcium regulates intercellular communication through gap junctions and triggers the terminal differentiation ...
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Decoding the Ca2+ Signal for Salt Tolerance
Nature Reviews Molecular Cell Biology, 2022Paulina Strzyz
exaly