Results 211 to 220 of about 770,691 (293)

Select NSAIDs enhance peripheral nerve growth and calcium signaling through PPARγ activation. [PDF]

Mol Cell Neurosci
Tusnim J, Padhi S, Chelala K, O'Connor JP, Pfister BJ, Firestein BL, Grasman JM.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Mediodorsal thalamus of alcohol-dependent mice shows genetic and physiological adaptations and alcohol-biased calcium signaling. [PDF]

Neuropharmacology
Martin JC, Reeves KC, Carter KA, Davis M, Schneider A, Meade E, Lebonville CL, Nimitvilai-Roberts S, Hoffman M, Woodward JJ, Loewinger G, Smith RJ, Lopez MF, Becker HC, Mulholland PJ, Rinker JA.   +15 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

TAOK2 controls synaptic plasticity and anxiety via ERK and calcium signaling. [PDF]

iScience
Ma W, Warnhoff I, Stephan M, Ma X, Dehne K, Volkmann P, Kannaiyan N, Brankatschk B, Jensen N, Rossner MJ, Scheuss V, Wehr MC.   +11 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The Multifaceted Role of Calcium Signaling in Regulated Necrosis. [PDF]

Biomolecules
Perez-Rivera E, Plasencia C, Ros U.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Orai1- and STIM1-mediated calcium signaling controls PD-L1 expression and modulates antitumor immunity in oral cancer. [PDF]

J Physiol Sci
Yamashita E, Ishikawa S, Mizuno Y, Iida Y, Mochizuki M, Nagasako A, Endo M, Osawa K, Kimura Y, Fujita T, Yokoyama U, Mitsudo K, Ishikawa Y, Umemura M.   +13 more
europepmc   +1 more source