Disrupted TFEB/GDNF-cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice. [PDF]
Adv Sci (Weinh)ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Yao L +5 more
europepmc +2 more sources
Glial syncytial control fields and the low-frequency resonome of the human brain. [PDF]
Front Hum NeurosciBallús Santacana A.
europepmc +1 more source
Novel Na<sub>V</sub>1.6-Mitochondrial Complexes in Retinal Astrocyte Pockets Sequester GABA. [PDF]
GliaHolden JM, Calkins DJ.
europepmc +1 more source
The 3-Body Problem: How Astrocytes May Govern Plasticity. [PDF]
NeuroscientistWatanabe A, Guo C, Sjöström PJ.
europepmc +1 more source
Astrocyte heterogeneity and hierarchical information flow: reframing glial computation. [PDF]
Front Cell NeurosciPérez O, Schummers J, López-Hidalgo M.
europepmc +1 more source
The IL-17A modulating astrocytic activity was associated with the electroacupuncture-mediated improvement of sensorimotor ability after stroke. [PDF]
Chin MedYau Y +7 more
europepmc +1 more source
Astrocyte store-operated calcium entry is required for centrally mediated neuropathic pain. [PDF]
Pain RepProkhorenko MA, Smyth JT.
europepmc +1 more source
Convergent Astrocytic Failure in Parkinson's Disease: A System-Level Model of Pathogenesis and Treatment. [PDF]
Mol NeurobiolAbdelaziz AM, Fawzy MN, Shokr MM.
europepmc +1 more source
Astrocytes amplify cortical dopamine to encode winning memory in male mice. [PDF]
Nat CommunNoh K +6 more
europepmc +1 more source
Astrocyte-Targeted Biomarkers for Calcitonin Gene-Related Peptide-Related Neurovascular Disorders: Insights from Calcium and Metabolic Profiling. [PDF]
ACS OmegaPhatruengdet T, Niraso B, Phiwchai I.
europepmc +1 more source