Results 31 to 40 of about 31,071 (248)
Amyloid pathology disrupts gliotransmitter release in astrocytes.
PLoS Computational Biology, 2022 Accumulation of amyloid-beta (Aβ) is associated with synaptic dysfunction and destabilization of astrocytic calcium homeostasis. A growing body of evidence support astrocytes as active modulators of synaptic transmission via calcium-mediated ...
Anup Gopalakrishna Pillai +1 more
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Visualizing Calcium Signaling in Astrocytes [PDF]
Science Signaling, 2010 Astrocyte signaling is apparent in movies of rat brain astrocytes cultured with fluorescent calcium indicator dyes.
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Frontiers in Cellular Neuroscience, 2023 The astroCAST is a novel solution to a longstanding challenge in neuroscience research: the specialized analysis of astrocytic calcium events within fluorescence time-series imaging. Distinct from existing neuron-centric tools, astroCAST is adept at detecting and clustering astrocytic calcium events based on their unique spatiotemporal characteristics,
Jan Philipp Reising +8 more
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Opioid-Mediated Astrocyte–Neuron Signaling in the Nucleus Accumbens
Cells, 2019 Major hallmarks of astrocyte physiology are the elevation of intracellular calcium in response to neurotransmitters and the release of neuroactive substances (gliotransmitters) that modulate neuronal activity.
Michelle Corkrum +4 more
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Astrocyte as Spatiotemporal Integrating Detector of Neuronal Activity
Frontiers in Physiology, 2019 The functional role of astrocyte calcium signaling in brain information processing was intensely debated in recent decades. This interest was motivated by high resolution imaging techniques showing highly developed structure of distal astrocyte processes.
Susan Yu. Gordleeva +3 more
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Calcium Signals in Astrocyte Microdomains, a Decade of Great Advances [PDF]
Frontiers in Cellular Neuroscience, 2021 The glial cells astrocytes have long been recognized as important neuron-supporting elements in brain development, homeostasis, and metabolism. After the discovery that the reciprocal communication between astrocytes and neurons is a fundamental mechanism in the modulation of neuronal synaptic communication, over the last two decades astrocytes became ...
Annamaria Lia +12 more
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Activity changes in neuron-astrocyte networks in culture under the effect of norepinephrine. [PDF]
PLoS ONE, 2018 The concerted activity of neuron-glia networks is responsible for the fascinating dynamics of brain functions. Although these networks have been extensively investigated using a variety of experimental (in vivo and in vitro) and theoretical models, the ...
Yasmin Bar El +3 more
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Determinants of functional coupling between astrocytes and respiratory neurons in the pre-Bötzinger complex. [PDF]
PLoS ONE, 2011 Respiratory neuronal network activity is thought to require efficient functioning of astrocytes. Here, we analyzed neuron-astrocyte communication in the pre-Bötzinger Complex (preBötC) of rhythmic slice preparations from neonatal mice. In astrocytes that
Christian Schnell +2 more
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Modulation of intercellular calcium signaling in astrocytes by extracellular calcium and magnesium [PDF]
Glia, 2003 AbstractThe extracellular concentrations of Ca2+ and Mg2+ are well known to play important roles in the function of the central nervous system. We examined the effects of extracellular Ca2+ and Mg2+ on ATP release and intercellular signaling in astrocytes.
Charles, Stout, Andrew, Charles
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Astrocyte-induced synchronization of neural network activity [PDF]
Известия высших учебных заведений: Прикладная нелинейная динамикаThe purpose of this work is to study the role of mechanisms of astrocytic regulation of synaptic transmission in the processes of synchronization formation in signaling of neural networks by mathematical modeling methods. Methods.
Ermolaeva, Anastasia Viktorovna +2 more
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