Results 21 to 30 of about 31,071 (248)

Astrocyte Calcium Signaling. [PDF]

Cold Spring Harb Perspect Biol
Astrocytes are predominant glial cells that tile the central nervous system and participate in well-established functional and morphological interactions with neurons, blood vessels, and other glia. These ubiquitous cells display rich intracellular Ca2+ signaling, which has now been studied for over 30 years.
Ahrens MB, Khakh BS, Poskanzer KE.
europepmc   +3 more sources

Calcium Dynamics in Astrocyte-Neuron Communication from Intracellular to Extracellular Signaling

Cells
Astrocytic calcium signaling is a central mechanism of neuron-glia communication that operates across multiple spatial and temporal scales. Traditionally, research has focused on intracellular Ca2+ oscillations that regulate gliotransmitter release, ion ...
Agnieszka Nowacka, Maciej Śniegocki, Ewa A. Ziółkowska   +2 more
doaj   +3 more sources

Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices

STAR Protocols, 2022
Summary: Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a protocol to monitor and manipulate astrocyte calcium activity from mouse amygdala slices.
Angel Baudon, Etienne Clauss-Creusot, Pascal Darbon, Ryan Patwell, Valery Grinevich, Alexandre Charlet   +5 more
doaj   +1 more source

Astrocyte calcium signaling and epilepsy [PDF]

Glia, 2012
AbstractStudies performed over the last decade, in both animal models and human epilepsy, support the view that a defective K+ buffering due to an altered expression of K+ and aquaporin channels in astrocytes represents a possible causative factor of the pathological neuronal hyperexcitability in the epileptic brain.
Carmignoto, Giorgio, Haydon, Philip G.
openaire   +2 more sources

Correction: Advances in astrocytic calcium signaling research

Frontiers in Cellular Neuroscience
Yuzhu Chen, Yejun Ye, Joyce Jia, Binhao Long, Tingting Dou, Xingke Yan   +5 more
doaj   +5 more sources

Potassium dependent regulation of astrocyte water permeability is mediated by cAMP signaling. [PDF]

PLoS ONE, 2012
Astrocytes express potassium and water channels to support dynamic regulation of potassium homeostasis. Potassium kinetics can be modulated by aquaporin-4 (AQP4), the essential water channel for astrocyte water permeability regulation.
Yutong Song, Eli Gunnarson
doaj   +1 more source

Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels

Nature Communications, 2023
Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood.
Michaela M. Novakovic, Kirill S. Korshunov, Rogan A. Grant, Megan E. Martin, Hiam A. Valencia, G. R. Scott Budinger, Jelena Radulovic, Murali Prakriya   +7 more
doaj   +1 more source

Laser-Induced Nuclear Damage Signaling and Communication in Astrocyte Networks Through Parp-Dependent Calcium Oscillations

Frontiers in Physics, 2021
Astrocytes are known to respond to various perturbations with oscillations of calcium, including to cellular injury. Less is known about astrocytes’ ability to detect DNA/nuclear damage.
Nicole M. Wakida, Ryan D. Ha, Edward K. Kim, Xiangduo Kong, Kyoko Yokomori, Michael W. Berns, Michael W. Berns   +6 more
doaj   +1 more source

Activity-dependent modulation of synapse-regulating genes in astrocytes

eLife, 2021
Astrocytes regulate the formation and function of neuronal synapses via multiple signals; however, what controls regional and temporal expression of these signals during development is unknown.
Isabella Farhy-Tselnicker, Matthew M Boisvert, Hanqing Liu, Cari Dowling, Galina A Erikson, Elena Blanco-Suarez, Chen Farhy, Maxim N Shokhirev, Joseph R Ecker, Nicola J Allen   +9 more
doaj   +1 more source

Modeling the relationship between neuronal activity and the BOLD signal: contributions from astrocyte calcium dynamics

Scientific Reports, 2023
Functional magnetic resonance imaging relies on the coupling between neuronal and vascular activity, but the mechanisms behind this coupling are still under discussion.
Federico Tesler, Marja-Leena Linne, Alain Destexhe   +2 more
doaj   +1 more source