Results 41 to 50 of about 1,396,802 (284)
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3 [PDF]
, 2008 Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (SCA3, MJD1) protein.
X. Chen +15 more
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Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation In Vivo with CalExflox Mice. [PDF]
, 2021 Astrocytes exist throughout the CNS and affect neural circuits and behavior through intracellular Ca2+ signaling. Studying the function(s) of astrocyte Ca2+ signaling has proven difficult because of the paucity of tools to achieve selective attenuation ...
Moye, Stefanie L +2 more
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Modulation of intercellular calcium signaling in astrocytes by extracellular calcium and magnesium [PDF]
Glia, 2003 AbstractThe extracellular concentrations of Ca2+ and Mg2+ are well known to play important roles in the function of the central nervous system. We examined the effects of extracellular Ca2+ and Mg2+ on ATP release and intercellular signaling in astrocytes.
Charles, Stout, Andrew, Charles
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Dopamine-induced calcium signaling in olfactory bulb astrocytes [PDF]
Scientific Reports, 2020 AbstractIt is well established that astrocytes respond to the major neurotransmitters glutamate and GABA with cytosolic calcium rises, whereas less is known about the effect of dopamine on astroglial cells. In the present study, we used confocal calcium imaging in mouse brain slices of the olfactory bulb, a brain region with a large population of ...
Fischer, Timo +2 more
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Astrocyte-induced synchronization of neural network activity [PDF]
Известия высших учебных заведений: Прикладная нелинейная динамикаThe purpose of this work is to study the role of mechanisms of astrocytic regulation of synaptic transmission in the processes of synchronization formation in signaling of neural networks by mathematical modeling methods. Methods.
Ermolaeva, Anastasia Viktorovna +2 more
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Glutamate mediated astrocytic filtering of neuronal activity. [PDF]
PLoS Computational Biology, 2014 Neuron-astrocyte communication is an important regulatory mechanism in various brain functions but its complexity and role are yet to be fully understood.
Gilad Wallach +6 more
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Complexity and Versatility of Calcium Signaling and Dynamics [PDF]
, 2021 The calcium ion is a universal second messenger mediating a wide range of dynamic cellular functions, such as exocytosis, contraction, transcription, and proliferation.
Torre, Vincent
core
Calcium Signaling and Gliotransmission in Normal vs. Reactive Astrocytes [PDF]
Frontiers in Pharmacology, 2012 A prominent area of neuroscience research over the past 20 years has been the acute modulation of neuronal synaptic activity by Ca(2+)-dependent release of the transmitters ATP, D-serine, and glutamate (called gliotransmitters) by astrocytes. Although the physiological relevance of this mechanism is under debate, emerging evidence suggests that there ...
Agulhon, Cendra +5 more
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Frontiers in Neurology, 2020 Methamphetamine (METH) use, referred to as methamphetamine use disorder (MUD), results in neurocognitive decline, a characteristic shared with HIV-associated neurocognitive disorders (HAND).
Irma E. Cisneros +2 more
doaj +1 more source
The Role of Astrocytic Calcium Signaling in the Aged Prefrontal Cortex [PDF]
Frontiers in Cellular Neuroscience, 2018 Aging is a lifelong process characterized by cognitive decline putatively due to structural and functional changes of neural circuits of the brain. Neuron-glial signaling is a fundamental component of structure and function of circuits of the brain, and yet its possible role in aging remains elusive.
Sónia Guerra-Gomes +18 more
openaire +4 more sources