Results 41 to 50 of about 6,142,155 (360)
Biomolecules, 2023 MAdCAM-1 binds to integrin α4β7, which mediates the rolling and arrest of circulating lymphocytes upon the vascular endothelia during lymphocytic homing.
Dongshan Sun +4 more
doaj +1 more source
Calcium Signaling in ß-cell Physiology and Pathology: A Revisit
International Journal of Molecular Sciences, 2019 Pancreatic beta (β) cell dysfunction results in compromised insulin release and, thus, failed regulation of blood glucose levels. This forms the backbone of the development of diabetes mellitus (DM), a disease that affects a significant portion of the ...
Christiane Klec +4 more
semanticscholar +1 more source
Mapping the spatiotemporal dynamics of calcium signaling in cellular neural networks using optical flow [PDF]
, 2010 An optical flow gradient algorithm was applied to spontaneously forming net- works of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling with single pixel resolution.
A. Cornell-Bell +37 more
core +5 more sources
Inherent rhythm of smooth muscle cells in rat mesenteric arterioles: an eigensystem formulation [PDF]
Phys. Rev. E 93, 042415 (2016), 2016 On the basis of experimental data and mathematical equations in the literature, we remodel the ionic dynamics of smooth muscle cells (SMCs) as an eigensystem formulation, which is valid for investigating finite variations of variables from the equilibrium like in common experimental operations.
arxiv +1 more source
Calcium Signaling and Reactive Oxygen Species in Mitochondria
Circulation Research, 2018 In heart failure, alterations of Na+ and Ca2+ handling, energetic deficit, and oxidative stress in cardiac myocytes are important pathophysiological hallmarks. Mitochondria are central to these processes because they are the main source for ATP, but also
E. Bertero, C. Maack
semanticscholar +1 more source
Examining the Effect of Introducing a Link from Electrical Excitation to Calcium Dynamics in a Cardiomyocyte [PDF]
, 2016 Calcium dysregulation is a significant cause of fatal cardiac arrythmias, but it is an incompletely understood phenomenon and difficult to predict. Cardiac calcium levels can be modeled as a system of partial differential equations linking the electrical
Angeloff, Kallista +6 more
core +2 more sources
Molecular Players of EF-hand Containing Calcium Signaling Event in Plants
International Journal of Molecular Sciences, 2019 Ca2+ is a universal second messenger that plays a pivotal role in diverse signaling mechanisms in almost all life forms. Since the evolution of life from an aquatic to a terrestrial environment, Ca2+ signaling systems have expanded and diversified ...
T. Mohanta +5 more
semanticscholar +1 more source
Fundamentals of Cellular Calcium Signaling: A Primer.
Cold Spring Harbor Perspectives in Biology, 2019 Ionized calcium (Ca2+) is the most versatile cellular messenger. All cells use Ca2+ signals to regulate their activities in response to extrinsic and intrinsic stimuli.
M. Bootman, G. Bultynck
semanticscholar +1 more source
Noxious Iron–Calcium Connections in Neurodegeneration
Frontiers in Neuroscience, 2019 Iron and calcium share the common feature of being essential for normal neuronal function. Iron is required for mitochondrial function, synaptic plasticity, and the development of cognitive functions whereas cellular calcium signals mediate ...
Marco Tulio Núñez +2 more
doaj +1 more source
TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Cancer of the pancreas is highly heterogeneous. Improvement of diagnosis and prognosis requires the discovery of new biomarkers and new methods of classification.
D. Crottès +6 more
semanticscholar +1 more source