Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion [PDF]
In many cell types agonist-receptor activation leads to a rapid and transient release of Ca(2+) from intracellular stores via activation of inositol 1,4,5 trisphosphate (InsP(3)) receptors (InsP(3)Rs).
Arnoult, Christophe +38 more
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Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]
Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
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The calcium connection: exploring the intricacies of calcium signaling in plant-microbe interactions
The process of plant immune response is orchestrated by intracellular signaling molecules. Since plants are devoid of a humoral system, they develop extensive mechanism of pathogen recognition, signal perception, and intricate cell signaling for their ...
Neelam Prabha Negi +6 more
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Calcium signaling in osteoclasts
It has long been known that many bone diseases, including osteoporosis, involve abnormalities in osteoclastic bone resorption. As a result, there has been intense study of the mechanisms that regulate both the differentiation and bone resorbing function of osteoclast cells.
Hwang, Sung-Yong, Putney, James W.
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Intracellular calcium signaling [PDF]
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
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Calcium at the Crossroads of Signaling [PDF]
### Calcium Signals: A Central Paradigm in Stimulus–Response Coupling Cells must respond to an array of environmental and developmental cues. The signaling networks that have evolved to generate appropriate cellular responses are varied and are normally composed of elements that include ...
Dale, Sanders +3 more
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Study of calcium sparks in skeletal and smooth muscle cells in normal and pathological conditions [PDF]
mTOR signaling influence a wide range of cellular process including protein synthesis (Iadevaia et al., 2012; Ma and Blenis, 2009; Thoreen et al., 2012), lipids synthesis (Lamming and Sabatini, 2013), transcription (Dibble and Manning, 2013; Vazquez ...
López, Rubén
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Noxious Iron–Calcium Connections in Neurodegeneration
Iron and calcium share the common feature of being essential for normal neuronal function. Iron is required for mitochondrial function, synaptic plasticity, and the development of cognitive functions whereas cellular calcium signals mediate ...
Marco Tulio Núñez +2 more
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Microglial calcium signaling is attuned to neuronal activity in awake mice
Microglial calcium signaling underlies a number of key physiological and pathological processes in situ, but has not been studied in vivo in awake mice.
Anthony D Umpierre +5 more
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Comparative analysis of calcium spikes upon activation of serotonin(1A) and purinergic receptors. [PDF]
Calcium signaling represents one of the most important signaling cascades in cells and regulates diverse processes such as exocytosis, muscle contraction and relaxation, gene expression and cell growth.
Roopali Saxena +2 more
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