Results 31 to 40 of about 1,971,191 (306)

High Metabolic Function and Resilience of NKG2A-Educated NK Cells

open access: yesFrontiers in Immunology, 2020
Natural killer (NK) cells are an important component of the innate immune system for the control of intracellular pathogens and cancer cells. NK cells demonstrate heterogeneous expression of inhibitory surface receptors.
Andrew J. Highton   +9 more
doaj   +1 more source

Calcium Signaling and Neurodegeneration [PDF]

open access: yesActa Naturae, 2010
Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and spinocerebellar ataxias (SCA) are very important both for fundamental science and for practical medicine. Despite extensive research into the causes of these diseases, clinical researchers have had
openaire   +4 more sources

Cellular and nuclear morphology…and calcium signaling: revealing the interplay between structure and function [PDF]

open access: yes, 2012
Poster presentation: Calcium plays a pivotal role in relaying electrical signals of the cell to subcellular compartments, such as the nucleus. Since this one ion type is used by the cell for many processes a neuron needs to establish finely tuned calcium
Queisser, Sean Gillian   +14 more
core   +1 more source

Melamine promotes calcium crystal formation in three-dimensional microfluidic device

open access: yesScientific Reports, 2019
Melamine, which induces proximal tubular (PT) cell damage has a greater nephrotoxic effect when combined with cyanuric and uric acids; however, it is unknown whether such effect can stimulate calcium phosphate (CaP)/calcium oxalate (CaOx) stone formation.
Farai Gombedza   +6 more
doaj   +1 more source

Vascular Calcification and Stone Disease: A New Look towards the Mechanism

open access: yesJournal of Cardiovascular Development and Disease, 2015
Calcium phosphate (CaP) crystals are formed in pathological calcification as well as during stone formation. Although there are several theories as to how these crystals can develop through the combined interactions of biochemical and biophysical factors,
Allen J. Yiu   +3 more
doaj   +1 more source

Intracellular calcium signaling [PDF]

open access: yesJournal of Cell Science, 2002
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
openaire   +2 more sources

Calcium at the Crossroads of Signaling [PDF]

open access: yesThe Plant Cell, 2002
### Calcium Signals: A Central Paradigm in Stimulus–Response Coupling Cells must respond to an array of environmental and developmental cues. The signaling networks that have evolved to generate appropriate cellular responses are varied and are normally composed of elements that include ...
Dale, Sanders   +3 more
openaire   +2 more sources

Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]

open access: yes, 2009
Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
core   +1 more source

Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]

open access: yes, 2013
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
core   +1 more source

Fluid Flow-Induced Calcium Response in Osteoclasts: Signaling Pathways [PDF]

open access: yes, 2014
Intracellular calcium oscillation and its downstream signaling in osteoclasts is believed to play critical roles in regulating bone resorption. Our previous study demonstrated that fluid shear stress (FSS) induced more calcium responsive peaks in the ...
Liu, Chenglin   +6 more
core   +1 more source

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