Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
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Cellular and nuclear morphology…and calcium signaling: revealing the interplay between structure and function [PDF]
Poster presentation: Calcium plays a pivotal role in relaying electrical signals of the cell to subcellular compartments, such as the nucleus. Since this one ion type is used by the cell for many processes a neuron needs to establish finely tuned calcium
Queisser, Sean Gillian +4 more
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Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V +31 more
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High Metabolic Function and Resilience of NKG2A-Educated NK Cells
Natural killer (NK) cells are an important component of the innate immune system for the control of intracellular pathogens and cancer cells. NK cells demonstrate heterogeneous expression of inhibitory surface receptors.
Andrew J. Highton +9 more
doaj +1 more source
Calcium Signaling and Neurodegeneration [PDF]
Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and spinocerebellar ataxias (SCA) are very important both for fundamental science and for practical medicine. Despite extensive research into the causes of these diseases, clinical researchers have had
openaire +4 more sources
Information transfer in signaling pathways : a study using coupled simulated and experimental data [PDF]
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown.
Kummer, U. (Ursula) +7 more
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Melamine promotes calcium crystal formation in three-dimensional microfluidic device
Melamine, which induces proximal tubular (PT) cell damage has a greater nephrotoxic effect when combined with cyanuric and uric acids; however, it is unknown whether such effect can stimulate calcium phosphate (CaP)/calcium oxalate (CaOx) stone formation.
Farai Gombedza +6 more
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Vascular Calcification and Stone Disease: A New Look towards the Mechanism
Calcium phosphate (CaP) crystals are formed in pathological calcification as well as during stone formation. Although there are several theories as to how these crystals can develop through the combined interactions of biochemical and biophysical factors,
Allen J. Yiu +3 more
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Intracellular calcium signaling [PDF]
In excitable cells, the major pathway for Ca2+ influx is via highly Ca2+-selective voltage-gated Ca2+ channels (VGCC). The original alphabetical nomenclature was replaced recently with standard numerical nomenclature: Cav1.1-1.4, Cav2.1-2.3, Cav3.1-3.3.
Martha C, Nowycky, Andrew P, Thomas
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Calcium at the Crossroads of Signaling [PDF]
### Calcium Signals: A Central Paradigm in Stimulus–Response Coupling Cells must respond to an array of environmental and developmental cues. The signaling networks that have evolved to generate appropriate cellular responses are varied and are normally composed of elements that include ...
Dale, Sanders +3 more
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