Results 11 to 20 of about 518,632 (310)
X-ROS Signaling Depends on Length-Dependent Calcium Buffering by Troponin
Cells, 2021 The stretching of a cardiomyocyte leads to the increased production of reactive oxygen species that increases ryanodine receptor open probability through a process termed X-ROS signaling.
Sarita Limbu +4 more
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Crystals, 2023 The increased utilization of titanium dioxide (TiO2) nanoparticles (TNPs) in various industrial and consumer products has raised concerns regarding its harmful effect due to its accumulation within the different systems of the human body.
Onyebuchi C. Ukaeje +1 more
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Calcium Signalling: Calcium Goes Global [PDF]
Current Biology, 2002 Recent evidence suggests that multiple calcium-releasing messengers might be activated simultaneously to regulate patterns of intracellular calcium signalling. In this way, agonists might use different messenger cocktails to encode specific signals and target selected processes.
Genazzani, Armando A., Thorn, Peter
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Frontiers in Cell and Developmental Biology, 2020 In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei +8 more
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NAADP Signaling: New Kids on the Block
Cells, 2022 Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of ...
Andreas H. Guse
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Calcium Signaling and Cytotoxicity [PDF]
Environmental Health Perspectives, 1999 The divalent calcium cation Ca(2+) is used as a major signaling molecule during cell signal transduction to regulate energy output, cellular metabolism, and phenotype. The basis to the signaling role of Ca(2+) is an intricate network of cellular channels and transporters that allow a low resting concentration of Ca(2+) in the cytosol of the cell ([Ca(2+
G E, Kass, S, Orrenius
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Lipid Signaling During Gamete Maturation
Frontiers in Cell and Developmental Biology, 2022 Cell lipids are differentially distributed in distinct organelles and within the leaflets of the bilayer. They can further form laterally defined sub-domains within membranes with important signaling functions.
Sherif Mostafa +4 more
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Calcium signaling in lymphocytes [PDF]
Current Opinion in Immunology, 2008 In cells of the immune system, calcium signals are essential for diverse cellular functions including differentiation, effector function, and gene transcription. After the engagement of immunoreceptors such as T-cell and B-cell antigen receptors and the Fc receptors on mast cells and NK cells, the intracellular concentration of calcium ions is ...
Masatsugu, Oh-hora, Anjana, Rao
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Cell, 1995 Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
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Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3 [PDF]
, 2008 Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (SCA3, MJD1) protein.
X. Chen +15 more
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