Results 41 to 50 of about 1,856,966 (308)

Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]

open access: yes, 2009
Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
core   +1 more source

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion [PDF]

open access: yes, 2004
In many cell types agonist-receptor activation leads to a rapid and transient release of Ca(2+) from intracellular stores via activation of inositol 1,4,5 trisphosphate (InsP(3)) receptors (InsP(3)Rs).
Arnoult, Christophe   +38 more
core   +1 more source

The calcium connection: exploring the intricacies of calcium signaling in plant-microbe interactions

open access: yesFrontiers in Plant Science, 2023
The process of plant immune response is orchestrated by intracellular signaling molecules. Since plants are devoid of a humoral system, they develop extensive mechanism of pathogen recognition, signal perception, and intricate cell signaling for their ...
Neelam Prabha Negi   +6 more
doaj   +1 more source

Interplay Between Calcium and AMPK Signaling in Human Cytomegalovirus Infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Calcium signaling and the AMP-activated protein kinase (AMPK) signaling networks broadly regulate numerous aspects of cell biology. Human Cytomegalovirus (HCMV) infection has been found to actively manipulate the calcium-AMPK signaling axis to support ...
Diana M. Dunn, Joshua Munger
doaj   +1 more source

Calcium signaling in osteoclasts

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011
It has long been known that many bone diseases, including osteoporosis, involve abnormalities in osteoclastic bone resorption. As a result, there has been intense study of the mechanisms that regulate both the differentiation and bone resorbing function of osteoclast cells.
Hwang, Sung-Yong, Putney, James W.
openaire   +2 more sources

Study of calcium sparks in skeletal and smooth muscle cells in normal and pathological conditions [PDF]

open access: yes, 2016
mTOR signaling influence a wide range of cellular process including protein synthesis (Iadevaia et al., 2012; Ma and Blenis, 2009; Thoreen et al., 2012), lipids synthesis (Lamming and Sabatini, 2013), transcription (Dibble and Manning, 2013; Vazquez ...
López, Rubén
core   +1 more source

Noxious Iron–Calcium Connections in Neurodegeneration

open access: yesFrontiers in Neuroscience, 2019
Iron and calcium share the common feature of being essential for normal neuronal function. Iron is required for mitochondrial function, synaptic plasticity, and the development of cognitive functions whereas cellular calcium signals mediate ...
Marco Tulio Núñez   +2 more
doaj   +1 more source

Quantification of the density of cooperative neighboring synapses required to evoke endocannabinoid signaling [PDF]

open access: yes, 2014
The spatial pattern of synapse activation may impact on synaptic plasticity. This applies to the synaptically-evoked endocannabinoid-mediated short-term depression at the parallel fiber (PF) to Purkinje cell synapse, the occurrence of which requires ...
Pachoud, B   +10 more
core   +1 more source

Microglial calcium signaling is attuned to neuronal activity in awake mice

open access: yeseLife, 2020
Microglial calcium signaling underlies a number of key physiological and pathological processes in situ, but has not been studied in vivo in awake mice.
Anthony D Umpierre   +5 more
doaj   +1 more source

Comparative analysis of calcium spikes upon activation of serotonin(1A) and purinergic receptors. [PDF]

open access: yesPLoS ONE, 2012
Calcium signaling represents one of the most important signaling cascades in cells and regulates diverse processes such as exocytosis, muscle contraction and relaxation, gene expression and cell growth.
Roopali Saxena   +2 more
doaj   +1 more source

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