Results 21 to 30 of about 1,856,966 (308)

Calcium Signalling: Calcium Goes Global [PDF]

open access: yesCurrent Biology, 2002
Recent evidence suggests that multiple calcium-releasing messengers might be activated simultaneously to regulate patterns of intracellular calcium signalling. In this way, agonists might use different messenger cocktails to encode specific signals and target selected processes.
Genazzani, Armando A., Thorn, Peter
openaire   +5 more sources

Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia

open access: yesFrontiers in Cell and Developmental Biology, 2020
In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei   +8 more
doaj   +1 more source

NAADP Signaling: New Kids on the Block

open access: yesCells, 2022
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of ...
Andreas H. Guse
doaj   +1 more source

Calcium Signalling in Pericytes [PDF]

open access: yesJournal of Vascular Research, 2014
Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists of arteriolar and venular networks located upstream and downstream of the capillaries.
Theodor, Burdyga, Lyudmyla, Borysova
openaire   +2 more sources

Lipid Signaling During Gamete Maturation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cell lipids are differentially distributed in distinct organelles and within the leaflets of the bilayer. They can further form laterally defined sub-domains within membranes with important signaling functions.
Sherif Mostafa   +4 more
doaj   +1 more source

Calcium Signaling and Cytotoxicity [PDF]

open access: yesEnvironmental Health Perspectives, 1999
The divalent calcium cation Ca(2+) is used as a major signaling molecule during cell signal transduction to regulate energy output, cellular metabolism, and phenotype. The basis to the signaling role of Ca(2+) is an intricate network of cellular channels and transporters that allow a low resting concentration of Ca(2+) in the cytosol of the cell ([Ca(2+
G E, Kass, S, Orrenius
openaire   +2 more sources

Calcium signaling [PDF]

open access: yesCell, 1995
Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
openaire   +3 more sources

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3 [PDF]

open access: yes, 2008
Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (SCA3, MJD1) protein.
X. Chen   +15 more
core   +1 more source

Complexity and Versatility of Calcium Signaling and Dynamics [PDF]

open access: yes, 2021
The calcium ion is a universal second messenger mediating a wide range of dynamic cellular functions, such as exocytosis, contraction, transcription, and proliferation.
Torre, Vincent
core  

Novel Mutations in a Lethal Case of Lymphomatous Adult T Cell Lymphoma with Cryptic Myocardial Involvement

open access: yesCurrent Oncology, 2021
The autopsy of a 65-year-old diabetic African American male revealed significant left myocardial involvement by adult T-cell leukemia/lymphoma (ATLL) despite normal pre-mortem fluorodeoxyglucose (FDG) uptake by positron emission tomography/computed ...
Taraneh Hashemi Zonouz   +3 more
doaj   +1 more source

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