Results 121 to 130 of about 76,724 (208)

Soybean Inositol Polyphosphate 5‐Phosphatase 8 Confers Salt Tolerance by Reducing Sodium Influx Through Inositol 1,4,5‐Trisphosphate Signalling

Plant, Cell &Environment, Volume 49, Issue 7, Page 4420-4434, July 2026.
ABSTRACT Evidence suggests that the metabolism of inositol and its derivatives may be involved in various biological processes including salt tolerance, but there has been limited understanding. Ectopic expression of Gs5PTase8, an inositol polyphosphate 5‐phosphatase cloned from wild soybean (Glycine soja), significantly enhanced salt tolerance in ...
Qi Jia, Yuan Chen, Defeng Kong, Hanyu Fan, Song Sun, Yuhang Liu, Jiahui Fu, Man‐Wah Li, Fuk‐Ling Wong, Qinghua Li, Kangjing Liang, Hon‐Ming Lam, Wen‐Xiong Lin   +12 more
wiley   +1 more source

Phenotypic expansion of CALM1/2-associated disorders to include neurologic phenotypes without arrhythmia. [PDF]

Hum Mol Genet
Hoang HD, Spillmann RC, Wegner DJ, Tedesco MG, Brohus M, Novelli A, Stregapede F, Rogaia D, Troiani S, Lesinski J, Yuan W, Fielder SM, Zhang B, Morrison S, Regmi S, Foti MRS, Baldridge D, Silverman GA, Undiagnosed Diseases Network, Shea P, Dickson P, Wambach JA, Overgaard MT, Jensen HH, Olsen A, Prontera P, Shashi V, Pak SC, Schedl T.   +28 more
europepmc   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

Calmodulin assists during co-translational folding of the K_V7.2 channel calcium responsive domain. [PDF]

Protein Sci
Muguruza-Montero A, Tait JR, M-Alicante S, Metola A, Nuñez E, Urrutia J, Sunderlíková V, Katranidis A, von Heijne G, Tans SJ, Villarroel A.   +10 more
europepmc   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

The role of IP₃R and TRPC3 channels in vasoconstriction and hypertension. [PDF]

Pflugers Arch
Moraes RDA, Alves QL, da Silva LB, de Jesus RLC, Silva DF.   +4 more
europepmc   +1 more source

Microbial Metabolite‐Stimulated Bitter Taste Receptor T2R14 Signaling Is Modulated by CFTR Interactions

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Bitter taste receptors (T2Rs) play an important role in physiological and cellular responses. Bitter tasting chemicals and microbial metabolites can bind to T2R14, which enables interactions between T2R14 and specific intracellular domains of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel.
Tejas Gupte, Nisha Singh, Vikram Bhatia, Kavisha Arora, Shayan Amiri, Paul Fernyhough, Anjaparavanda P. Naren, Shyamala Dakshinamurti, Prashen Chelikani   +8 more
wiley   +1 more source

¹H^N, ¹³C, and ¹⁵N resonance assignments of Ca²⁺-calmodulin bound to a BP2 peptide derived from the sheep STRA6 vitamin A transporter (residues 625-656). [PDF]

Biomol NMR Assign
Cook ME, Varney KM, Zhuang X, Yazici AT, Mancia F, Weber DJ.   +5 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploitation of CREB signaling by HTLV-1 and BLV: A central axis in viral persistence and leukemogenesis. [PDF]

Med Oncol
Farjami Z, Akbarin MM.
europepmc   +1 more source