Results 141 to 150 of about 76,724 (208)

MiR‐30a‐5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β‐catenin pathway

Epilepsia Open, Volume 11, Issue 3, Page 983-1002, June 2026.
Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang, Xu Zhang, Jingjing Guo, Yuanxin Wei, Jinzi Li   +4 more
wiley   +1 more source

Identification of Antioxidant and Anti-Inflammatory Activity of Sea Cucumber (<i>Holothuria tubulosa</i>) Active Peptides by a Combined Approach of Omics Data and Bioinformatics Analysis. [PDF]

Mar Drugs
La Paglia L, Vazzana M, Mauro M, Dumas F, Urso A, Simon S, Drahos L, Vizzini A.   +7 more
europepmc   +1 more source

Eucalyptus camaldulensis Extract Mediated Green Synthesis of Iron Oxide Nanoparticles and In Vitro and In Vivo Biological Screening, and Detailed Molecular Docking Analysis

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Eucalyptus camaldulensis extract mediated green synthesis of IONPs and In vitro and In vivo Biological Screening, and Detailed Molecular Docking Analysis. ABSTRACT Natural products and their secondary metabolites have long been known as good bioresources in the synthesis of nanomaterials.
Abdur Rauf, Arshad Iqbal, Shahkar Usama, Imran Ullah, Walaa F. Alsanie, Abdulhakeem S. Alamri, Zuneera Akram, Rahaf Ajaj, Naveed Muhammad, Zubair Ahmad, Jaseem Ahmad, Mohammed Mansour Quradha   +11 more
wiley   +1 more source

Genome-Wide Identification and Characterization of the Calmodulin-Binding Transcription Activators (CAMTA) Gene Family in <i>Brassica</i> U-Triangle Species and Its Potential Role in Response to Phytohormones and Abiotic Stresses. [PDF]

Plants (Basel)
Wang Q, Chen S, Li H, Niu P, Wang X, Zhao H, Wan H, Qu C, Xu D.   +8 more
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Commentary on: direct binding of calmodulin to the cytosolic C-terminal regions of sweet/umami taste receptors. [PDF]

J Biochem
Misaka T.
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Dopamine D2 Receptors, D1/D2 Receptor Heteromers and CaMKII Signaling in the Neurobiology of Drug Addiction. [PDF]

Mol Neurobiol
Jia W, He X, Cheng A, He Y, Zhao F, Fukunaga K, Zhao W.   +6 more
europepmc   +1 more source

Dysregulation of Non‐Muscle Myosin IIA Assembly and Phosphorylation in S100A4 Null Mouse Lens

Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.
This study identifies S100A4 as a critical regulator of NMIIA assembly, phosphorylation, and actin cytoskeletal organization in the ocular lens. Loss of S100A4 disrupts lens fiber cell architecture and impairs lens transparency, revealing a previously unrecognized role for S100A4 in maintaining lens homeostasis and structural integrity.
Rupalatha Maddala, Levi K. Lankford, Nikolai P. Skiba, Ponugoti V. Rao   +3 more
wiley   +1 more source

Natural genetic variation in calcium sensor genes as a novel resource for abiotic stress tolerance in crops. [PDF]

Front Plant Sci
Issah AK, Wang Y, Azupio S, Zhang H, Chu J, Sayibu W, Xie Q, Jiang X.   +7 more
europepmc   +1 more source