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The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
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Emerging concepts of reactive oxygen species functions in plants. [PDF]
Foyer CH.
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Calcium Signaling Dysregulation as a Convergent Mechanism in Anesthetic-Induced Developmental Neurotoxicity. [PDF]
Dong C +4 more
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Functional consequences of calmodulin variants identified among schizophrenia patients and controls. [PDF]
Jensen HH +15 more
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Unravelıng non-canonıcal Wnt sıgnalıng ın neural development and dısorders: a revıew of Wnt/PCP and Wnt/ca<sup>²⁺</sup> pathways. [PDF]
Palabiyik AA, Palabiyik E.
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Two calmodulin binding elements contribute distinctly to TRPA1 calcium desensitization. [PDF]
Quevedo G +4 more
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Functional Calmodulin States Are Selected from an Electrostatically Tuned Free Energy Landscape. [PDF]
Tayhan B +3 more
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PEST sequences in calmodulin-binding proteins
Molecular and Cellular Biochemistry, 1995Many short-lived proteins which are devoid of proteolytic activity contain PEST sequences which are segments along the polypeptide chain that are rich in proline (P), glutamate (E), serine (S) and threonine (T). These designated PEST sequences are believed to be putative intramolecular signals for rapid proteolytic degradation.
Junor A Barnes +2 more
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