Results 181 to 190 of about 193,718 (292)

Long-term follow-up of patients with catecholaminergic polymorphic ventricular tachycardia related to a novel <i>CALM2</i> variant. [PDF]

J Cardiol Cases
Ohno S, Kato K, Fukuyama M, Hirono K, Nishida K, Horie M.   +5 more
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

TRPV1 from the TRP family: Structure, function, implication in autoimmune diseases and potential therapies. [PDF]

Channels (Austin)
Bejoma T, Pan Y, Zhao Q.
europepmc   +1 more source

Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. [PDF]

, 2016
Rattan, Satish
core   +2 more sources

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

The Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder, Tomas Stary, Gergő Bitay, Norbert Nagy, Axel Loewe   +4 more
wiley   +1 more source

Exploitation of CREB signaling by HTLV-1 and BLV: A central axis in viral persistence and leukemogenesis. [PDF]

Med Oncol
Farjami Z, Akbarin MM.
europepmc   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Genome-Wide Identification and Characterization of the Calmodulin-Binding Transcription Activators (CAMTA) Gene Family in <i>Brassica</i> U-Triangle Species and Its Potential Role in Response to Phytohormones and Abiotic Stresses. [PDF]

Plants (Basel)
Wang Q, Chen S, Li H, Niu P, Wang X, Zhao H, Wan H, Qu C, Xu D.   +8 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Double-Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections. [PDF]

CNS Neurosci Ther
Faraji N, Abavisani M, Ebadpour N, Karav S, Kesharwani P, Sahebkar A.   +5 more
europepmc   +1 more source