Results 81 to 90 of about 417,246 (251)

Editorial: Dietary Strategies for Healthy Aging—Caloric Restriction and Beyond

open access: yesFrontiers in Nutrition, 2022
Sebastian J. Hofer, Sergio Davinelli
doaj   +1 more source

Effects of Caloric Restriction on Delaying the Aging Process

open access: yesمجله دانشکده پزشکی اصفهان, 2013
The molecular mechanisms of aging are the subject of extensive research and have facilitated potential interventions to delay aging and age-related degenerative diseases in humans.
Omolbanin Kafeshani   +2 more
doaj  

Effect of modest caloric restriction on oxidative stress in women, a randomized trial.

open access: yesPLoS ONE, 2012
ObjectivesIt is not established to what extent caloric intake must be reduced to lower oxidative stress in humans. The aim of this study was to determine the effect of short-term, moderate caloric restriction on markers of oxidative stress and ...
Maciej S Buchowski   +5 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Restricted vs. Standard Caloric Intake in Critically Ill Patients with Refeeding Syndrome: An Evidence-Based Case Report

open access: yesJurnal Penyakit Dalam Indonesia
Refeeding syndrome is a different clinical symptom and metabolic disorder that occur during the reintroduction of nutrition in chronically malnourished patients. Calorie restriction can increase survival and reduce mortality rates.
Sukma Hapsari, Rabbinu Rangga Pribadi
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Hepatic metabolic reprogramming in male mice during short-term caloric restriction involves enhanced glucocorticoid rhythms

open access: yesNature Communications
Caloric restriction prolongs lifespan and preserves health across species, with feeding times synchronized to day–night cycles further maximizing benefits. However, the mechanisms linking diet, diurnal rhythms, and lifespan remain unclear.
Konstantinos Makris   +14 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

MicroRNA-203 regulates caveolin-1 in breast tissue during caloric restriction

open access: yes, 2012
Caloric restriction has been shown to increase lifespan in several organisms and to delay onset of age-related diseases. The transcriptional response to caloric restriction has been studied for mRNAs, while the microRNA signature following caloric ...
Lim, Meng K.   +6 more
core   +1 more source

Effect of 8 Weeks of High Intensity Interval Training (HIIT) With and Without Calorie Restriction on Gene Expression of Caspase-3 and Caspase-9 Proteins in Male Rats

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2020
Background and Aim Apoptosis or programmed death is active biological process and reversible that the balance between growth and cell death in various tissues, particularly myocardial tissue is essential role.
Mohammadreza Zarali   +3 more
doaj  

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